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Chemical tools to define and manipulate interferon-inducible Ubl protease USP18.
Davis GJ, Omole AO, Jung Y, Rut W, Holewinski R, Suazo KF, Kim HR, Yang M, Andresson T, Drag M, Yoo E. Davis GJ, et al. Among authors: holewinski r. bioRxiv [Preprint]. 2024 Apr 8:2024.04.08.588544. doi: 10.1101/2024.04.08.588544. bioRxiv. 2024. PMID: 38645224 Free PMC article. Preprint.
Covalent Inhibition by a Natural Product-Inspired Latent Electrophile.
Byun DP, Ritchie J, Jung Y, Holewinski R, Kim HR, Tagirasa R, Ivanic J, Weekley CM, Parker MW, Andresson T, Yoo E. Byun DP, et al. Among authors: holewinski r. J Am Chem Soc. 2023 May 24;145(20):11097-11109. doi: 10.1021/jacs.3c00598. Epub 2023 May 15. J Am Chem Soc. 2023. PMID: 37183434 Free PMC article.
Loss of NAT10 disrupts enhancer organization via p300 mislocalization and suppresses transcription of genes necessary for metastasis progression.
Amin R, Ha NH, Qiu T, Holewinski R, Lam KC, Lopès A, Liu H, Tran AD, Lee MP, Gamage ST, Andresson T, Goldszmid RS, Meier JL, Hunter KW. Amin R, et al. Among authors: holewinski r. bioRxiv [Preprint]. 2024 Jan 29:2024.01.24.577116. doi: 10.1101/2024.01.24.577116. bioRxiv. 2024. PMID: 38410432 Free PMC article. Preprint.
Investigating the NRAS 5' UTR as a target for small molecules.
Balaratnam S, Torrey ZR, Calabrese DR, Banco MT, Yazdani K, Liang X, Fullenkamp CR, Seshadri S, Holewinski RJ, Andresson T, Ferré-D'Amaré AR, Incarnato D, Schneekloth JS Jr. Balaratnam S, et al. Among authors: holewinski rj. Cell Chem Biol. 2023 Jun 15;30(6):643-657.e8. doi: 10.1016/j.chembiol.2023.05.004. Epub 2023 May 30. Cell Chem Biol. 2023. PMID: 37257453
NeuroLINCS Proteomics: Defining human-derived iPSC proteomes and protein signatures of pluripotency.
Matlock AD, Vaibhav V, Holewinski R, Venkatraman V, Dardov V, Manalo DM, Shelley B, Ornelas L, Banuelos M, Mandefro B, Escalante-Chong R, Li J, Finkbeiner S, Fraenkel E, Rothstein J, Thompson L, Sareen D, Svendsen CN; NIH NeuroLINCS Consortium; Van Eyk JE. Matlock AD, et al. Among authors: holewinski r. Sci Data. 2023 Jan 11;10(1):24. doi: 10.1038/s41597-022-01687-7. Sci Data. 2023. PMID: 36631473 Free PMC article.
MYC assembles and stimulates topoisomerases 1 and 2 in a "topoisome".
Das SK, Kuzin V, Cameron DP, Sanford S, Jha RK, Nie Z, Rosello MT, Holewinski R, Andresson T, Wisniewski J, Natsume T, Price DH, Lewis BA, Kouzine F, Levens D, Baranello L. Das SK, et al. Among authors: holewinski r. Mol Cell. 2022 Jan 6;82(1):140-158.e12. doi: 10.1016/j.molcel.2021.11.016. Epub 2021 Dec 9. Mol Cell. 2022. PMID: 34890565 Free PMC article.
Comparative Proteomic Analysis of HPV(+) Oropharyngeal Squamous Cell Carcinoma Recurrence.
Ho AS, Robinson A, Shon W, Laury A, Raedschelders K, Venkatraman V, Holewinski R, Zhang Y, Shiao SL, Chen MM, Mallen-St Clair J, Lin DC, Zumsteg ZS, Van Eyk JE. Ho AS, et al. Among authors: holewinski r. J Proteome Res. 2022 Jan 7;21(1):200-208. doi: 10.1021/acs.jproteome.1c00757. Epub 2021 Nov 30. J Proteome Res. 2022. PMID: 34846153
39 results