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Increased frequency of CHD1 deletions in prostate cancers of African American men is associated with rapid disease progression without inducing homologous recombination deficiency.
Szallasi Z, Diossy M, Tisza V, Li H, Sahgal P, Zhou J, Sztupinszki Z, Young D, Nuosome D, Kuo C, Jiang J, Chen Y, Ebner R, Sesterhenn I, Moncur J, Chesnut G, Petrovics G, T Klus G, Valcz G, Nuzzo P, Ribli D, Börcsök J, Prósz A, Krzystanek M, Ried T, Szüts D, Rizwan K, Kaochar S, Pathania S, D'Andrea A, Csabai I, Srivastava S, Freedman M, Dobi A, Spisak S. Szallasi Z, et al. Among authors: krzystanek m. Res Sq [Preprint]. 2024 Apr 1:rs.3.rs-3995251. doi: 10.21203/rs.3.rs-3995251/v1. Res Sq. 2024. PMID: 38645014 Free PMC article. Preprint.
Detection of Molecular Signatures of Homologous Recombination Deficiency in Prostate Cancer with or without BRCA1/2 Mutations.
Sztupinszki Z, Diossy M, Krzystanek M, Borcsok J, Pomerantz MM, Tisza V, Spisak S, Rusz O, Csabai I, Freedman ML, Szallasi Z. Sztupinszki Z, et al. Among authors: krzystanek m. Clin Cancer Res. 2020 Jun 1;26(11):2673-2680. doi: 10.1158/1078-0432.CCR-19-2135. Epub 2020 Feb 18. Clin Cancer Res. 2020. PMID: 32071115 Free PMC article.
A subset of lung cancer cases shows robust signs of homologous recombination deficiency associated genomic mutational signatures.
Diossy M, Sztupinszki Z, Borcsok J, Krzystanek M, Tisza V, Spisak S, Rusz O, Timar J, Csabai I, Fillinger J, Moldvay J, Pedersen AG, Szuts D, Szallasi Z. Diossy M, et al. Among authors: krzystanek m. NPJ Precis Oncol. 2021 Jun 18;5(1):55. doi: 10.1038/s41698-021-00199-8. NPJ Precis Oncol. 2021. PMID: 34145376 Free PMC article.
The genomic imprint of cancer therapies helps timing the formation of metastases.
Németh E, Krzystanek M, Reiniger L, Ribli D, Pipek O, Sztupinszki Z, Glasz T, Csabai I, Moldvay J, Szallasi Z, Szüts D. Németh E, et al. Among authors: krzystanek m. Int J Cancer. 2019 Aug 1;145(3):694-704. doi: 10.1002/ijc.32159. Epub 2019 Feb 18. Int J Cancer. 2019. PMID: 30694556 Free article.
Breast cancer brain metastases show increased levels of genomic aberration-based homologous recombination deficiency scores relative to their corresponding primary tumors.
Diossy M, Reiniger L, Sztupinszki Z, Krzystanek M, Timms KM, Neff C, Solimeno C, Pruss D, Eklund AC, Tóth E, Kiss O, Rusz O, Cserni G, Zombori T, Székely B, Kulka J, Tímár J, Csabai I, Szallasi Z. Diossy M, et al. Among authors: krzystanek m. Ann Oncol. 2018 Sep 1;29(9):1948-1954. doi: 10.1093/annonc/mdy216. Ann Oncol. 2018. PMID: 29917049 Free PMC article.
Overexpression of BLM promotes DNA damage and increased sensitivity to platinum salts in triple-negative breast and serous ovarian cancers.
Birkbak NJ, Li Y, Pathania S, Greene-Colozzi A, Dreze M, Bowman-Colin C, Sztupinszki Z, Krzystanek M, Diossy M, Tung N, Ryan PD, Garber JE, Silver DP, Iglehart JD, Wang ZC, Szuts D, Szallasi Z, Richardson AL. Birkbak NJ, et al. Among authors: krzystanek m. Ann Oncol. 2018 Apr 1;29(4):903-909. doi: 10.1093/annonc/mdy049. Ann Oncol. 2018. PMID: 29452344 Free PMC article.
A comprehensive survey of the mutagenic impact of common cancer cytotoxics.
Szikriszt B, Póti Á, Pipek O, Krzystanek M, Kanu N, Molnár J, Ribli D, Szeltner Z, Tusnády GE, Csabai I, Szallasi Z, Swanton C, Szüts D. Szikriszt B, et al. Among authors: krzystanek m. Genome Biol. 2016 May 9;17:99. doi: 10.1186/s13059-016-0963-7. Genome Biol. 2016. PMID: 27161042 Free PMC article.
127 results