Supuran CT - Search Results

1

Discovery and Mechanistic Studies of Dual-Target Hits for Carbonic Anhydrase IX and VEGFR-2 as Potential Agents for Solid Tumors: X-ray, In Vitro, In Vivo, and In Silico Investigations of Coumarin-Based Thiazoles.

Hefny SM, El-Moselhy TF, El-Din N, Giovannuzzi S, Bin Traiki T, Vaali-Mohammed MA, El-Dessouki AM, Yamaguchi K, Sugiura M, Shaldam MA, Supuran CT, Abdulla MH, Eldehna WM, Tawfik HO. Hefny SM, et al. Among authors: supuran ct. J Med Chem. 2024 May 9;67(9):7406-7430. doi: 10.1021/acs.jmedchem.4c00239. Epub 2024 Apr 20. J Med Chem. 2024. PMID: 38642371

2

Carbonic anhydrase inhibitors: water-soluble 4-sulfamoylphenylthioureas as topical intraocular pressure-lowering agents with long-lasting effects.

Casini A, Scozzafava A, Mincione F, Menabuoni L, Ilies MA, Supuran CT. Casini A, et al. Among authors: supuran ct. J Med Chem. 2000 Dec 14;43(25):4884-92. doi: 10.1021/jm001051+. J Med Chem. 2000. PMID: 11123998

3

Carbonic anhydrase inhibitors.

Supuran CT, Scozzafava A, Casini A. Supuran CT, et al. Med Res Rev. 2003 Mar;23(2):146-89. doi: 10.1002/med.10025. Med Res Rev. 2003. PMID: 12500287 Review.

4

Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozyme IX with aromatic and heterocyclic sulfonamides.

Vullo D, Franchi M, Gallori E, Pastorek J, Scozzafava A, Pastorekova S, Supuran CT. Vullo D, et al. Among authors: supuran ct. Bioorg Med Chem Lett. 2003 Mar 24;13(6):1005-9. doi: 10.1016/s0960-894x(03)00091-x. Bioorg Med Chem Lett. 2003. PMID: 12643899

5

Hydroxyurea is a carbonic anhydrase inhibitor.

Scozzafava A, Supuran CT. Scozzafava A, et al. Among authors: supuran ct. Bioorg Med Chem. 2003 May 15;11(10):2241-6. doi: 10.1016/s0968-0896(03)00112-3. Bioorg Med Chem. 2003. PMID: 12713833

6

Carbonic anhydrase inhibitors: E7070, a sulfonamide anticancer agent, potently inhibits cytosolic isozymes I and II, and transmembrane, tumor-associated isozyme IX.

Abbate F, Casini A, Owa T, Scozzafava A, Supuran CT. Abbate F, et al. Among authors: supuran ct. Bioorg Med Chem Lett. 2004 Jan 5;14(1):217-23. doi: 10.1016/j.bmcl.2003.09.062. Bioorg Med Chem Lett. 2004. PMID: 14684331

7

Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with EMATE, a dual inhibitor of carbonic anhydrases and steroid sulfatase.

Abbate F, Winum JY, Potter BV, Casini A, Montero JL, Scozzafava A, Supuran CT. Abbate F, et al. Among authors: supuran ct. Bioorg Med Chem Lett. 2004 Jan 5;14(1):231-4. doi: 10.1016/j.bmcl.2003.09.064. Bioorg Med Chem Lett. 2004. PMID: 14684333

8

Carbonic anhydrase inhibitors. Inhibition of mitochondrial isozyme V with aromatic and heterocyclic sulfonamides.

Vullo D, Franchi M, Gallori E, Antel J, Scozzafava A, Supuran CT. Vullo D, et al. Among authors: supuran ct. J Med Chem. 2004 Feb 26;47(5):1272-9. doi: 10.1021/jm031057+. J Med Chem. 2004. PMID: 14971907

9

Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozyme IX with fluorine-containing sulfonamides. The first subnanomolar CA IX inhibitor discovered.

Vullo D, Scozzafava A, Pastorekova S, Pastorek J, Supuran CT. Vullo D, et al. Among authors: supuran ct. Bioorg Med Chem Lett. 2004 May 3;14(9):2351-6. doi: 10.1016/j.bmcl.2004.01.095. Bioorg Med Chem Lett. 2004. PMID: 15081039

10

Carbonic anhydrase inhibitors: synthesis and topical intraocular pressure lowering effects of fluorine-containing inhibitors devoid of enhanced reactivity.

de Leval X, Ilies M, Casini A, Dogné JM, Scozzafava A, Masini E, Mincione F, Starnotti M, Supuran CT. de Leval X, et al. Among authors: supuran ct. J Med Chem. 2004 May 20;47(11):2796-804. doi: 10.1021/jm031116j. J Med Chem. 2004. PMID: 15139757

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