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Feasibility, safety and tolerability of the CREB-binding protein/β-catenin inhibitor OP-724 in patients with advanced primary biliary cholangitis: an investigator-initiated, open-label, non-randomised, two-centre, phase 1 study.
Kimura M, Ogawa E, Harada K, Imamura J, Saio M, Ikura Y, Yatsuhashi H, Murata K, Miura K, Ieiri I, Tanaka A, Kimura K. Kimura M, et al. BMJ Open Gastroenterol. 2022 Nov;9(1):e001001. doi: 10.1136/bmjgast-2022-001001. BMJ Open Gastroenterol. 2022. PMID: 36442892 Free PMC article. Clinical Trial.
Potential utility of l-carnitine for preventing liver tumors derived from metabolic dysfunction-associated steatohepatitis.
Lyu J, Okada H, Sunagozaka H, Kawaguchi K, Shimakami T, Nio K, Murai K, Shirasaki T, Yoshida M, Arai K, Yamashita T, Tanaka T, Harada K, Takamura T, Kaneko S, Yamashita T, Honda M. Lyu J, et al. Hepatol Commun. 2024 Apr 12;8(5):e0425. doi: 10.1097/HC9.0000000000000425. eCollection 2024 May 1. Hepatol Commun. 2024. PMID: 38619434 Free PMC article.
Selenoprotein P deficiency protects against immobilization-induced muscle atrophy by suppressing atrophy-related E3 ubiquitin ligases.
Abuduwaili H, Kamoshita K, Ishii KA, Takahashi K, Abuduyimiti T, Qifang L, Isobe Y, Goto H, Nakano Y, Takeshita Y, Takayama H, Harada K, Takamura T. Abuduwaili H, et al. Am J Physiol Endocrinol Metab. 2023 Jun 1;324(6):E542-E552. doi: 10.1152/ajpendo.00270.2022. Epub 2023 Mar 22. Am J Physiol Endocrinol Metab. 2023. PMID: 36947851
PAC1 Deficiency Protects Obese Male Mice From Immobilization-Induced Muscle Atrophy by Suppressing FoxO-Atrogene Axis.
Li Q, Ishii KA, Kamoshita K, Takahashi K, Abuduwaili H, Takayama H, Galicia-Medina CM, Tanida R, Ko Oo H, Gafiyatullina G, Yao X, Abuduyimiti T, Hamazaki J, Goto H, Nakano Y, Takeshita Y, Harada K, Murata S, Takamura T. Li Q, et al. Endocrinology. 2023 Apr 17;164(6):bqad065. doi: 10.1210/endocr/bqad065. Endocrinology. 2023. PMID: 37103220 Free PMC article.
Diabetes Accelerates Steatohepatitis in Mice: Liver Pathology and Single-Cell Gene Expression Signatures.
Abuduyimiti T, Goto H, Kimura K, Oshima Y, Tanida R, Kamoshita K, Leerach N, Abuduwaili H, Oo HK, Li Q, Galicia-Medina CM, Takayama H, Ishii KA, Nakano Y, Takeshita Y, Iba T, Naito H, Honda M, Harada K, Yamamoto Y, Takamura T. Abuduyimiti T, et al. Am J Pathol. 2024 May;194(5):693-707. doi: 10.1016/j.ajpath.2024.01.007. Epub 2024 Feb 1. Am J Pathol. 2024. PMID: 38309428 Free article.
112 results