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Novel hydrazone compounds with broad-spectrum antiplasmodial activity and synergistic interactions with antimalarial drugs.
Rosado-Quiñones AM, Colón-Lorenzo EE, Pala ZR, Bosch J, Kudyba K, Kudyba H, Leed SE, Roncal N, Baerga-Ortiz A, Roche-Lima A, Gerena Y, Fidock DA, Roth A, Vega-Rodríguez J, Serrano AE. Rosado-Quiñones AM, et al. Among authors: vega rodriguez j. Antimicrob Agents Chemother. 2024 Apr 19:e0164323. doi: 10.1128/aac.01643-23. Online ahead of print. Antimicrob Agents Chemother. 2024. PMID: 38639491 Free article.
The heat shock protein Hsc70-3 mediates an anti-apoptotic response critical for Plasmodium evasion of Anopheles gambiae immunity.
Alves E Silva TL, Canepa GE, Sweeney B, Hessab Alvarenga P, Zhao M, Vega-Rodríguez J, Molina-Cruz A, Barillas-Mury C. Alves E Silva TL, et al. Among authors: vega rodriguez j. Microbiol Spectr. 2023 Dec 12;11(6):e0094023. doi: 10.1128/spectrum.00940-23. Epub 2023 Nov 20. Microbiol Spectr. 2023. PMID: 37982627 Free PMC article.
Leishmania genetic exchange is mediated by IgM natural antibodies.
Serafim TD, Iniguez E, Barletta ABF, Cecilio P, Doehl JSP, Short M, Lack J, Nair V, Disotuar M, Wilson T, Coutinho-Abreu IV, Meneses C, Andersen J, Alves E Silva TL, Oliveira F, Vega-Rodriguez J, Barillas-Mury C, Ribeiro JMC, Beverley SM, Kamhawi S, Valenzuela JG. Serafim TD, et al. Among authors: vega rodriguez j. Nature. 2023 Nov;623(7985):149-156. doi: 10.1038/s41586-023-06655-8. Epub 2023 Oct 25. Nature. 2023. PMID: 37880367
Anopheles salivary apyrase regulates blood meal hemostasis and drives malaria parasite transmission.
Pala ZR, Alves E Silva TL, Minai M, Crews B, Patino-Martinez E, Carmona-Rivera C, Valenzuela-Leon PC, Martin-Martin I, Flores-Garcia Y, Cachau RE, Srivastava N, Moore IN, Alves DA, Kaplan MJ, Fischer E, Calvo E, Vega-Rodriguez J. Pala ZR, et al. Among authors: vega rodriguez j. bioRxiv [Preprint]. 2023 May 22:2023.05.22.541827. doi: 10.1101/2023.05.22.541827. bioRxiv. 2023. PMID: 37292610 Free PMC article. Preprint.
Single-Cell Transcriptomics To Define Plasmodium falciparum Stage Transition in the Mosquito Midgut.
Mohammed M, Dziedziech A, Sekar V, Ernest M, Alves E Silva TL, Balan B, Emami SN, Biryukova I, Friedländer MR, Jex A, Jacobs-Lorena M, Henriksson J, Vega-Rodriguez J, Ankarklev J. Mohammed M, et al. Among authors: vega rodriguez j. Microbiol Spectr. 2023 Feb 27;11(2):e0367122. doi: 10.1128/spectrum.03671-22. Online ahead of print. Microbiol Spectr. 2023. PMID: 36847501 Free PMC article.
Author Correction: A human monoclonal antibody blocks malaria transmission and defines a highly conserved neutralizing epitope on gametes.
Coelho CH, Tang WK, Burkhardt M, Galson JD, Muratova O, Salinas ND, Alves E Silva TL, Reiter K, MacDonald NJ, Nguyen V, Herrera R, Shimp R, Narum DL, Byrne-Steele M, Pan W, Hou X, Brown B, Eisenhower M, Han J, Jenkins BJ, Doritchamou JYA, Smelkinson MG, Vega-Rodríguez J, Trück J, Taylor JJ, Sagara I, Healy SA, Renn JP, Tolia NH, Duffy PE. Coelho CH, et al. Among authors: vega rodriguez j. Nat Commun. 2022 Aug 15;13(1):4797. doi: 10.1038/s41467-022-32574-9. Nat Commun. 2022. PMID: 35970895 Free PMC article. No abstract available.
42 results