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Atherosclerotic Plaque Epigenetic Age Acceleration Predicts a Poor Prognosis and Is Associated With Endothelial-to-Mesenchymal Transition in Humans.
Diez Benavente E, Hartman RJG, Sakkers TR, Wesseling M, Sloots Y, Slenders L, Boltjes A, Mol BM, de Borst GJ, de Kleijn DPV, Prange KHM, de Winther MPJ, Kuiper J, Civelek M, van der Laan SW, Horvath S, Onland-Moret NC, Mokry M, Pasterkamp G, den Ruijter HM. Diez Benavente E, et al. Among authors: horvath s. Arterioscler Thromb Vasc Biol. 2024 Jun;44(6):1419-1431. doi: 10.1161/ATVBAHA.123.320692. Epub 2024 Apr 18. Arterioscler Thromb Vasc Biol. 2024. PMID: 38634280 Free article.
Epigenetic predictor of age.
Bocklandt S, Lin W, Sehl ME, Sánchez FJ, Sinsheimer JS, Horvath S, Vilain E. Bocklandt S, et al. Among authors: horvath s. PLoS One. 2011;6(6):e14821. doi: 10.1371/journal.pone.0014821. Epub 2011 Jun 22. PLoS One. 2011. PMID: 21731603 Free PMC article.
Adipose co-expression networks across Finns and Mexicans identify novel triglyceride-associated genes.
Haas BE, Horvath S, Pietiläinen KH, Cantor RM, Nikkola E, Weissglas-Volkov D, Rissanen A, Civelek M, Cruz-Bautista I, Riba L, Kuusisto J, Kaprio J, Tusie-Luna T, Laakso M, Aguilar-Salinas CA, Pajukanta P. Haas BE, et al. Among authors: horvath s. BMC Med Genomics. 2012 Dec 6;5:61. doi: 10.1186/1755-8794-5-61. BMC Med Genomics. 2012. PMID: 23217153 Free PMC article.
Accelerated epigenetic aging in Down syndrome.
Horvath S, Garagnani P, Bacalini MG, Pirazzini C, Salvioli S, Gentilini D, Di Blasio AM, Giuliani C, Tung S, Vinters HV, Franceschi C. Horvath S, et al. Aging Cell. 2015 Jun;14(3):491-5. doi: 10.1111/acel.12325. Epub 2015 Feb 9. Aging Cell. 2015. PMID: 25678027 Free PMC article.
Acceleration of age-associated methylation patterns in HIV-1-infected adults.
Rickabaugh TM, Baxter RM, Sehl M, Sinsheimer JS, Hultin PM, Hultin LE, Quach A, Martínez-Maza O, Horvath S, Vilain E, Jamieson BD. Rickabaugh TM, et al. Among authors: horvath s. PLoS One. 2015 Mar 25;10(3):e0119201. doi: 10.1371/journal.pone.0119201. eCollection 2015. PLoS One. 2015. PMID: 25807146 Free PMC article.
Accelerated epigenetic aging in Werner syndrome.
Maierhofer A, Flunkert J, Oshima J, Martin GM, Haaf T, Horvath S. Maierhofer A, et al. Among authors: horvath s. Aging (Albany NY). 2017 Apr;9(4):1143-1152. doi: 10.18632/aging.101217. Aging (Albany NY). 2017. PMID: 28377537 Free PMC article.
Placental epigenetic clocks: estimating gestational age using placental DNA methylation levels.
Lee Y, Choufani S, Weksberg R, Wilson SL, Yuan V, Burt A, Marsit C, Lu AT, Ritz B, Bohlin J, Gjessing HK, Harris JR, Magnus P, Binder AM, Robinson WP, Jugessur A, Horvath S. Lee Y, et al. Among authors: horvath s. Aging (Albany NY). 2019 Jun 24;11(12):4238-4253. doi: 10.18632/aging.102049. Aging (Albany NY). 2019. PMID: 31235674 Free PMC article.
We show that epigenetic clocks derived from cord blood or other tissues do not accurately estimate GA in placental samples. While fundamentally different from Horvath's pan-tissue epigenetic clock, placental clocks closely track fetal age during development and may …
We show that epigenetic clocks derived from cord blood or other tissues do not accurately estimate GA in placental samples. While fundamenta …
A meta-analysis of genome-wide association studies of epigenetic age acceleration.
Gibson J, Russ TC, Clarke TK, Howard DM, Hillary RF, Evans KL, Walker RM, Bermingham ML, Morris SW, Campbell A, Hayward C, Murray AD, Porteous DJ, Horvath S, Lu AT, McIntosh AM, Whalley HC, Marioni RE. Gibson J, et al. Among authors: horvath s. PLoS Genet. 2019 Nov 18;15(11):e1008104. doi: 10.1371/journal.pgen.1008104. eCollection 2019 Nov. PLoS Genet. 2019. PMID: 31738745 Free PMC article.
Two commonly used measures, derived from DNA methylation, are Horvath-based (Horvath-EAA) and Hannum-based (Hannum-EAA) epigenetic age acceleration. ...We identified ten independent SNPs associated with Horvath-EAA, five of which are novel. We also report 21 …
Two commonly used measures, derived from DNA methylation, are Horvath-based (Horvath-EAA) and Hannum-based (Hannum-EAA) epigen …
1,281 results