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Page 1
Atherosclerotic Plaque Epigenetic Age Acceleration Predicts a Poor Prognosis and Is Associated With Endothelial-to-Mesenchymal Transition in Humans.
Diez Benavente E, Hartman RJG, Sakkers TR, Wesseling M, Sloots Y, Slenders L, Boltjes A, Mol BM, de Borst GJ, de Kleijn DPV, Prange KHM, de Winther MPJ, Kuiper J, Civelek M, van der Laan SW, Horvath S, Onland-Moret NC, Mokry M, Pasterkamp G, den Ruijter HM. Diez Benavente E, et al. Among authors: civelek m. Arterioscler Thromb Vasc Biol. 2024 Jun;44(6):1419-1431. doi: 10.1161/ATVBAHA.123.320692. Epub 2024 Apr 18. Arterioscler Thromb Vasc Biol. 2024. PMID: 38634280 Free article.
The WWOX gene modulates high-density lipoprotein and lipid metabolism.
Iatan I, Choi HY, Ruel I, Reddy MV, Kil H, Lee J, Odeh MA, Salah Z, Abu-Remaileh M, Weissglas-Volkov D, Nikkola E, Civelek M, Awan Z, Croce CM, Aqeilan RI, Pajukanta P, Aldaz CM, Genest J. Iatan I, et al. Among authors: civelek m. Circ Cardiovasc Genet. 2014 Aug;7(4):491-504. doi: 10.1161/CIRCGENETICS.113.000248. Epub 2014 May 28. Circ Cardiovasc Genet. 2014. PMID: 24871327 Free PMC article.
The Atherosclerosis Risk Variant rs2107595 Mediates Allele-Specific Transcriptional Regulation of HDAC9 via E2F3 and Rb1.
Prestel M, Prell-Schicker C, Webb T, Malik R, Lindner B, Ziesch N, Rex-Haffner M, Röh S, Viturawong T, Lehm M, Mokry M, den Ruijter H, Haitjema S, Asare Y, Söllner F, Najafabadi MG, Aherrahrou R, Civelek M, Samani NJ, Mann M, Haffner C, Dichgans M. Prestel M, et al. Among authors: civelek m. Stroke. 2019 Oct;50(10):2651-2660. doi: 10.1161/STROKEAHA.119.026112. Epub 2019 Sep 10. Stroke. 2019. PMID: 31500558
Genetic Regulation of Atherosclerosis-Relevant Phenotypes in Human Vascular Smooth Muscle Cells.
Aherrahrou R, Guo L, Nagraj VP, Aguhob A, Hinkle J, Chen L, Yuhl Soh J, Lue D, Alencar GF, Boltjes A, van der Laan SW, Farber E, Fuller D, Anane-Wae R, Akingbesote N, Manichaikul AW, Ma L, Kaikkonen MU, Björkegren JLM, Önengüt-Gümüşcü S, Pasterkamp G, Miller CL, Owens GK, Finn A, Navab M, Fogelman AM, Berliner JA, Civelek M. Aherrahrou R, et al. Among authors: civelek m. Circ Res. 2020 Dec 4;127(12):1552-1565. doi: 10.1161/CIRCRESAHA.120.317415. Epub 2020 Oct 12. Circ Res. 2020. PMID: 33040646 Free PMC article.
Sex-Stratified Gene Regulatory Networks Reveal Female Key Driver Genes of Atherosclerosis Involved in Smooth Muscle Cell Phenotype Switching.
Hartman RJG, Owsiany K, Ma L, Koplev S, Hao K, Slenders L, Civelek M, Mokry M, Kovacic JC, Pasterkamp G, Owens G, Björkegren JLM, den Ruijter HM. Hartman RJG, et al. Among authors: civelek m. Circulation. 2021 Feb 16;143(7):713-726. doi: 10.1161/CIRCULATIONAHA.120.051231. Epub 2021 Jan 27. Circulation. 2021. PMID: 33499648 Free PMC article.
Intersecting single-cell transcriptomics and genome-wide association studies identifies crucial cell populations and candidate genes for atherosclerosis.
Slenders L, Landsmeer LPL, Cui K, Depuydt MAC, Verwer M, Mekke J, Timmerman N, van den Dungen NAM, Kuiper J, de Winther MPJ, Prange KHM, Ma WF, Miller CL, Aherrahrou R, Civelek M, de Borst GJ, de Kleijn DPV, Asselbergs FW, den Ruijter HM, Boltjes A, Pasterkamp G, van der Laan SW, Mokry M. Slenders L, et al. Among authors: civelek m. Eur Heart J Open. 2021 Dec 21;2(1):oeab043. doi: 10.1093/ehjopen/oeab043. eCollection 2022 Jan. Eur Heart J Open. 2021. PMID: 35174364 Free PMC article.
Genetic Regulation of SMC Gene Expression and Splicing Predict Causal CAD Genes.
Aherrahrou R, Lue D, Perry RN, Aberra YT, Khan MD, Soh JY, Örd T, Singha P, Yang Q, Gilani H, Benavente ED, Wong D, Hinkle J, Ma L, Sheynkman GM, den Ruijter HM, Miller CL, Björkegren JLM, Kaikkonen MU, Civelek M. Aherrahrou R, et al. Among authors: civelek m. Circ Res. 2023 Feb 3;132(3):323-338. doi: 10.1161/CIRCRESAHA.122.321586. Epub 2023 Jan 4. Circ Res. 2023. PMID: 36597873 Free PMC article.
129 results