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Safety and efficacy of losmapimod in facioscapulohumeral muscular dystrophy (ReDUX4): a randomised, double-blind, placebo-controlled phase 2b trial.
Tawil R, Wagner KR, Hamel JI, Leung DG, Statland JM, Wang LH, Genge A, Sacconi S, Lochmüller H, Reyes-Leiva D, Diaz-Manera J, Alonso-Perez J, Muelas N, Vilchez JJ, Pestronk A, Gibson S, Goyal NA, Hayward LJ, Johnson N, LoRusso S, Freimer M, Shieh PB, Subramony SH, van Engelen B, Kools J, Leinhard OD, Widholm P, Morabito C, Moxham CM, Cadavid D, Mellion ML, Odueyungbo A, Tracewell WG, Accorsi A, Ronco L, Gould RJ, Shoskes J, Rojas LA, Jiang JG. Tawil R, et al. Lancet Neurol. 2024 May;23(5):477-486. doi: 10.1016/S1474-4422(24)00073-5. Lancet Neurol. 2024. PMID: 38631764 Clinical Trial.
Facioscapulohumeral muscular dystrophy.
Statland J, Tawil R. Statland J, et al. Among authors: tawil r. Neurol Clin. 2014 Aug;32(3):721-8, ix. doi: 10.1016/j.ncl.2014.04.003. Epub 2014 May 15. Neurol Clin. 2014. PMID: 25037087 Free PMC article. Review.
Facioscapulohumeral Dystrophy.
Wang LH, Tawil R. Wang LH, et al. Among authors: tawil r. Curr Neurol Neurosci Rep. 2016 Jul;16(7):66. doi: 10.1007/s11910-016-0667-0. Curr Neurol Neurosci Rep. 2016. PMID: 27215221 Review.
p38α Regulates Expression of DUX4 in a Model of Facioscapulohumeral Muscular Dystrophy.
Rojas LA, Valentine E, Accorsi A, Maglio J, Shen N, Robertson A, Kazmirski S, Rahl P, Tawil R, Cadavid D, Thompson LA, Ronco L, Chang AN, Cacace AM, Wallace O. Rojas LA, et al. Among authors: tawil r. J Pharmacol Exp Ther. 2020 Sep;374(3):489-498. doi: 10.1124/jpet.119.264689. Epub 2020 Jun 23. J Pharmacol Exp Ther. 2020. PMID: 32576599
Current Therapeutic Approaches in FSHD.
Wang LH, Tawil R. Wang LH, et al. Among authors: tawil r. J Neuromuscul Dis. 2021;8(3):441-451. doi: 10.3233/JND-200554. J Neuromuscul Dis. 2021. PMID: 33579868 Free PMC article. Review.
230 results