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Neoadjuvant chemotherapy is associated with suppression of the B cell-centered immune landscape in pancreatic ductal adenocarcinoma.
Rupp L, Dietsche I, Kießler M, Sommer U, Muckenhuber A, Steiger K, van Eijck CWF, Richter L, Istvanffy R, Jäger C, Friess H, van Eijck CHJ, Demir IE, Reyes CM, Schmitz M. Rupp L, et al. Among authors: friess h. Front Immunol. 2024 Apr 2;15:1378190. doi: 10.3389/fimmu.2024.1378190. eCollection 2024. Front Immunol. 2024. PMID: 38629072 Free PMC article.
Phenotype screens of murine pancreatic cancer identify a Tgf-α-Ccl2-paxillin axis driving human-like neural invasion.
Wang X, Istvanffy R, Ye L, Teller S, Laschinger M, Diakopoulos KN, Görgülü K, Li Q, Ren L, Jäger C, Steiger K, Muckenhuber A, Vilne B, Çifcibaşı K, Reyes CM, Yurteri Ü, Kießler M, Gürçınar IH, Sugden M, Yıldızhan SE, Sezerman OU, Çilingir S, Süyen G, Reichert M, Schmid RM, Bärthel S, Oellinger R, Krüger A, Rad R, Saur D, Algül H, Friess H, Lesina M, Ceyhan GO, Demir IE. Wang X, et al. Among authors: friess h. J Clin Invest. 2023 Nov 1;133(21):e166333. doi: 10.1172/JCI166333. J Clin Invest. 2023. PMID: 37607005 Free PMC article.
Dynamics and cytokinic regulation of immune cell infiltration in genetically engineered mouse models of pancreatic cancer dictate the sensitivity to immunotherapy.
Safak O, Wang S, Mota Reyes C, Gürcinar IH, Tokalov S, Cevik NC, Görgülü K, Yilmaz BS, Erdogan E, Ye L, Li Q, Sever EA, Özer S, Süyen G, Friess H, Ceyhan GO, Istvanffy R, Algül H, Demir IE. Safak O, et al. Among authors: friess h. Cancer Commun (Lond). 2024 Jan;44(1):178-182. doi: 10.1002/cac2.12496. Epub 2023 Oct 25. Cancer Commun (Lond). 2024. PMID: 37877813 Free PMC article. No abstract available.
Author Correction: Proteogenomic analysis reveals RNA as a source for tumor-agnostic neoantigen identification.
Tretter C, de Andrade Krätzig N, Pecoraro M, Lange S, Seifert P, von Frankenberg C, Untch J, Zuleger G, Wilhelm M, Zolg DP, Dreyer FS, Bräunlein E, Engleitner T, Uhrig S, Boxberg M, Steiger K, Slotta-Huspenina J, Ochsenreither S, von Bubnoff N, Bauer S, Boerries M, Jost PJ, Schenck K, Dresing I, Bassermann F, Friess H, Reim D, Grützmann K, Pfütze K, Klink B, Schröck E, Haller B, Kuster B, Mann M, Weichert W, Fröhling S, Rad R, Hiltensperger M, Krackhardt AM. Tretter C, et al. Among authors: friess h. Nat Commun. 2024 Mar 15;15(1):2364. doi: 10.1038/s41467-024-46724-8. Nat Commun. 2024. PMID: 38491045 Free PMC article. No abstract available.
Encapsulated cells expressing a chemotherapeutic activating enzyme allow the targeting of subtoxic chemotherapy and are safe and efficacious: data from two clinical trials in pancreatic cancer.
Löhr JM, Haas SL, Kröger JC, Friess HM, Höft R, Goretzki PE, Peschel C, Schweigert M, Salmons B, Gunzburg WH. Löhr JM, et al. Among authors: friess hm. Pharmaceutics. 2014 Aug 11;6(3):447-66. doi: 10.3390/pharmaceutics6030447. Pharmaceutics. 2014. PMID: 25116885 Free PMC article. Review.
1,217 results