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Detecting androgen receptor (AR), AR variant 7 (AR-V7), prostate-specific membrane antigen (PSMA), and prostate-specific antigen (PSA) gene expression in CTCs and plasma exosome-derived cfRNA in patients with metastatic castration-resistant prostate cancer (mCRPC) by integrating the VTX-1 CTC isolation system with the QIAGEN AdnaTest.
Liu HE, Vuppalapaty M, Hoerner CR, Bergstrom CP, Chiu M, Lemaire C, Che J, Kaur A, Dimmick A, Liu S, Metzner TJ, Araya M, Crouse S, Sprenger-Haussels M, Schlumpberger M, Leppert JT, Hauch S, Sollier E, Fan AC. Liu HE, et al. Among authors: vuppalapaty m. BMC Cancer. 2024 Apr 16;24(1):482. doi: 10.1186/s12885-024-12139-3. BMC Cancer. 2024. PMID: 38627648 Free PMC article.
BRAIDing receptors for cell-specific targeting.
Chen H, Lee SJ, Li R, Sura A, Suen N, Dilip A, Pomogov Y, Vuppalapaty M, Suen TT, Lu C, Post Y, Li Y. Chen H, et al. Among authors: vuppalapaty m. Elife. 2024 Jan 9;12:RP90221. doi: 10.7554/eLife.90221. Elife. 2024. PMID: 38193894 Free PMC article.
Therapeutic blood-brain barrier modulation and stroke treatment by a bioengineered FZD4-selective WNT surrogate in mice.
Ding J, Lee SJ, Vlahos L, Yuki K, Rada CC, van Unen V, Vuppalapaty M, Chen H, Sura A, McCormick AK, Tomaske M, Alwahabi S, Nguyen H, Nowatzke W, Kim L, Kelly L, Vollrath D, Califano A, Yeh WC, Li Y, Kuo CJ. Ding J, et al. Among authors: vuppalapaty m. Nat Commun. 2023 Jun 2;14(1):2947. doi: 10.1038/s41467-023-37689-1. Nat Commun. 2023. PMID: 37268690 Free PMC article.
Development of selective bispecific Wnt mimetics for bone loss and repair.
Fowler TW, Mitchell TL, Janda CY, Xie L, Tu S, Chen H, Zhang H, Ye J, Ouyang B, Yuan TZ, Lee SJ, Newman M, Tripuraneni N, Rego ES, Mutha D, Dilip A, Vuppalapaty M, Baribault H, Yeh WC, Li Y. Fowler TW, et al. Among authors: vuppalapaty m. Nat Commun. 2021 May 31;12(1):3247. doi: 10.1038/s41467-021-23374-8. Nat Commun. 2021. PMID: 34059688 Free PMC article.
Detection of EGFR Mutations in cfDNA and CTCs, and Comparison to Tumor Tissue in Non-Small-Cell-Lung-Cancer (NSCLC) Patients.
Liu HE, Vuppalapaty M, Wilkerson C, Renier C, Chiu M, Lemaire C, Che J, Matsumoto M, Carroll J, Crouse S, Hanft VR, Jeffrey SS, Di Carlo D, Garon EB, Goldman J, Sollier E. Liu HE, et al. Among authors: vuppalapaty m. Front Oncol. 2020 Oct 8;10:572895. doi: 10.3389/fonc.2020.572895. eCollection 2020. Front Oncol. 2020. PMID: 33117705 Free PMC article.
Fast and Label-Free Isolation of Circulating Tumor Cells from Blood: From a Research Microfluidic Platform to an Automated Fluidic Instrument, VTX-1 Liquid Biopsy System.
Lemaire CA, Liu SZ, Wilkerson CL, Ramani VC, Barzanian NA, Huang KW, Che J, Chiu MW, Vuppalapaty M, Dimmick AM, Carlo DD, Kochersperger ML, Crouse SC, Jeffrey SS, Englert RF, Hengstler S, Renier C, Sollier-Christen E. Lemaire CA, et al. Among authors: vuppalapaty m. SLAS Technol. 2018 Feb;23(1):16-29. doi: 10.1177/2472630317738698. SLAS Technol. 2018. PMID: 29355087