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Structural conservation of antibiotic interaction with ribosomes.
Paternoga H, Crowe-McAuliffe C, Bock LV, Koller TO, Morici M, Beckert B, Myasnikov AG, Grubmüller H, Nováček J, Wilson DN. Paternoga H, et al. Among authors: morici m. Nat Struct Mol Biol. 2023 Sep;30(9):1380-1392. doi: 10.1038/s41594-023-01047-y. Epub 2023 Aug 7. Nat Struct Mol Biol. 2023. PMID: 37550453 Free PMC article.
The cyclic octapeptide antibiotic argyrin B inhibits translation by trapping EF-G on the ribosome during translocation.
Wieland M, Holm M, Rundlet EJ, Morici M, Koller TO, Maviza TP, Pogorevc D, Osterman IA, Müller R, Blanchard SC, Wilson DN. Wieland M, et al. Among authors: morici m. Proc Natl Acad Sci U S A. 2022 May 10;119(19):e2114214119. doi: 10.1073/pnas.2114214119. Epub 2022 May 2. Proc Natl Acad Sci U S A. 2022. PMID: 35500116 Free PMC article.
Paenilamicins from the honey bee pathogen Paenibacillus larvae are context-specific translocation inhibitors of protein synthesis.
Koller TO, Berger MJ, Morici M, Paternoga H, Bulatov T, Di Stasi A, Dang T, Mainz A, Raulf K, Crowe-McAuliffe C, Scocchi M, Mardirossian M, Beckert B, Vázquez-Laslop N, Mankin A, Süssmuth RD, Wilson DN. Koller TO, et al. Among authors: morici m. bioRxiv [Preprint]. 2024 May 21:2024.05.21.595107. doi: 10.1101/2024.05.21.595107. bioRxiv. 2024. PMID: 38826346 Free PMC article. Preprint.
66 results