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A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects.
Yang XM, Yang Y, Yao BF, Ye PP, Xu Y, Peng SP, Yang YM, Shu P, Li PJ, Li S, Hu HL, Li Q, Song LL, Chen KG, Zhou HY, Zhang YH, Zhao FR, Tang BH, Zhang W, Zhang XF, Fu SM, Hao GX, Zheng Y, Shen JS, Xu YC, Jiang XR, Zhang LK, Tang RH, Zhao W. Yang XM, et al. Among authors: tang bh. Eur J Pharm Sci. 2023 Dec 1;191:106598. doi: 10.1016/j.ejps.2023.106598. Epub 2023 Sep 30. Eur J Pharm Sci. 2023. PMID: 37783378 Free article. Clinical Trial.
Machine Learning: A New Approach for Dose Individualization.
Li QY, Tang BH, Wu YE, Yao BF, Zhang W, Zheng Y, Zhou Y, van den Anker J, Hao GX, Zhao W. Li QY, et al. Among authors: tang bh. Clin Pharmacol Ther. 2024 Apr;115(4):727-744. doi: 10.1002/cpt.3049. Epub 2023 Sep 29. Clin Pharmacol Ther. 2024. PMID: 37713106 Review.
Use of Machine Learning for Dosage Individualization of Vancomycin in Neonates.
Tang BH, Zhang JY, Allegaert K, Hao GX, Yao BF, Leroux S, Thomson AH, Yu Z, Gao F, Zheng Y, Zhou Y, Capparelli EV, Biran V, Simon N, Meibohm B, Lo YL, Marques R, Peris JE, Lutsar I, Saito J, Jacqz-Aigrain E, van den Anker J, Wu YE, Zhao W. Tang BH, et al. Clin Pharmacokinet. 2023 Aug;62(8):1105-1116. doi: 10.1007/s40262-023-01265-z. Epub 2023 Jun 10. Clin Pharmacokinet. 2023. PMID: 37300630
80 results