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102 results

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Page 1
Integrative Profiling of T790M-Negative EGFR-Mutated NSCLC Reveals Pervasive Lineage Transition and Therapeutic Opportunities.
Chua KP, Teng YHF, Tan AC, Takano A, Alvarez JJS, Nahar R, Rohatgi N, Lai GGY, Aung ZW, Yeong JPS, Lim KH, Naeini MM, Kassam I, Jain A, Tan WL, Gogna A, Too CW, Kanesvaran R, Ng QS, Ang MK, Rajasekaran T, Anantham D, Phua GC, Tan BS, Lee YY, Wang L, Teo ASM, Khng AJ, Lim MJ, Suteja L, Toh CK, Lim WT, Iyer NG, Tam WL, Tan EH, Zhai W, Hillmer AM, Skanderup AJ, Tan DSW. Chua KP, et al. Among authors: tam wl. Clin Cancer Res. 2021 Nov 1;27(21):5939-5950. doi: 10.1158/1078-0432.CCR-20-4607. Epub 2021 Jul 14. Clin Cancer Res. 2021. PMID: 34261696 Free PMC article.
Oncogene-driven non-small cell lung cancers in patients with a history of smoking lack smoking-induced mutations.
Huang CY, Jiang N, Shen M, Lai GG, Tan AC, Jain A, Saw SP, Ang MK, Ng QS, Lim DW, Kanesvaran R, Tan EH, Tan WL, Ong BH, Chua KL, Anantham D, Takano AM, Lim KH, Tam WL, Sim NL, Skanderup AJ, Tan DS, Rozen SG. Huang CY, et al. Among authors: tam wl. Cancer Res. 2024 Apr 8. doi: 10.1158/0008-5472.CAN-23-2551. Online ahead of print. Cancer Res. 2024. PMID: 38587551
Genomic landscape of lung adenocarcinoma in East Asians.
Chen J, Yang H, Teo ASM, Amer LB, Sherbaf FG, Tan CQ, Alvarez JJS, Lu B, Lim JQ, Takano A, Nahar R, Lee YY, Phua CZJ, Chua KP, Suteja L, Chen PJ, Chang MM, Koh TPT, Ong BH, Anantham D, Hsu AAL, Gogna A, Too CW, Aung ZW, Lee YF, Wang L, Lim TKH, Wilm A, Choi PS, Ng PY, Toh CK, Lim WT, Ma S, Lim B, Liu J, Tam WL, Skanderup AJ, Yeong JPS, Tan EH, Creasy CL, Tan DSW, Hillmer AM, Zhai W. Chen J, et al. Among authors: tam wl. Nat Genet. 2020 Feb;52(2):177-186. doi: 10.1038/s41588-019-0569-6. Epub 2020 Feb 3. Nat Genet. 2020. PMID: 32015526
Deficiency of the splicing factor RBM10 limits EGFR inhibitor response in EGFR-mutant lung cancer.
Nanjo S, Wu W, Karachaliou N, Blakely CM, Suzuki J, Chou YT, Ali SM, Kerr DL, Olivas VR, Shue J, Rotow J, Mayekar MK, Haderk F, Chatterjee N, Urisman A, Yeo JC, Skanderup AJ, Tan AC, Tam WL, Arrieta O, Hosomichi K, Nishiyama A, Yano S, Kirichok Y, Tan DS, Rosell R, Okimoto RA, Bivona TG. Nanjo S, et al. Among authors: tam wl. J Clin Invest. 2022 Jul 1;132(13):e145099. doi: 10.1172/JCI145099. J Clin Invest. 2022. PMID: 35579943 Free PMC article.
Hypoxia-driven immunosuppression by Treg and type-2 conventional dendritic cells in HCC.
Suthen S, Lim CJ, Nguyen PHD, Dutertre CA, Lai HLH, Wasser M, Chua C, Lim TKH, Leow WQ, Loh TJ, Wan WK, Pang YH, Soon G, Cheow PC, Kam JH, Iyer S, Kow A, Tam WL, Shuen TWH, Toh HC, Dan YY, Bonney GK, Chan CY, Chung A, Goh BKP, Zhai W, Ginhoux F, Chow PKH, Albani S, Chew V. Suthen S, et al. Among authors: tam wl. Hepatology. 2022 Nov;76(5):1329-1344. doi: 10.1002/hep.32419. Epub 2022 Mar 17. Hepatology. 2022. PMID: 35184329
Dynamic phenotypic heterogeneity and the evolution of multiple RNA subtypes in hepatocellular carcinoma: the PLANET study.
Zhai W, Lai H, Kaya NA, Chen J, Yang H, Lu B, Lim JQ, Ma S, Chew SC, Chua KP, Alvarez JJS, Chen PJ, Chang MM, Wu L, Goh BKP, Chung AY, Chan CY, Cheow PC, Lee SY, Kam JH, Kow AW, Ganpathi IS, Chanwat R, Thammasiri J, Yoong BK, Ong DB, de Villa VH, Dela Cruz RD, Loh TJ, Wan WK, Zeng Z, Skanderup AJ, Pang YH, Madhavan K, Lim TK, Bonney G, Leow WQ, Chew V, Dan YY, Tam WL, Toh HC, Foo RS, Chow PK. Zhai W, et al. Among authors: tam wl. Natl Sci Rev. 2021 Oct 29;9(3):nwab192. doi: 10.1093/nsr/nwab192. eCollection 2022 Mar. Natl Sci Rev. 2021. PMID: 35382356 Free PMC article.
Dependency of NELF-E-SLUG-KAT2B epigenetic axis in breast cancer carcinogenesis.
Zhang J, Hu Z, Chung HH, Tian Y, Lau KW, Ser Z, Lim YT, Sobota RM, Leong HF, Chen BJ, Yeo CJ, Tan SYX, Kang J, Tan DEK, Sou IF, McClurg UL, Lakshmanan M, Vaiyapuri TS, Raju A, Wong ESM, Tergaonkar V, Rajarethinam R, Pathak E, Tam WL, Tan EY, Tee WW. Zhang J, et al. Among authors: tam wl. Nat Commun. 2023 Apr 28;14(1):2439. doi: 10.1038/s41467-023-38132-1. Nat Commun. 2023. PMID: 37117180 Free PMC article.
New High-Throughput Screening Identifies Compounds That Reduce Viability Specifically in Liver Cancer Cells That Express High Levels of SALL4 by Inhibiting Oxidative Phosphorylation.
Tan JL, Li F, Yeo JZ, Yong KJ, Bassal MA, Ng GH, Lee MY, Leong CY, Tan HK, Wu CS, Liu BH, Chan TH, Tan ZH, Chan YS, Wang S, Lim ZH, Toh TB, Hooi L, Low KN, Ma S, Kong NR, Stein AJ, Wu Y, Thangavelu MT, Suzuki A, Periyasamy G, Asara JM, Dan YY, Bonney GK, Chow EK, Lu GD, Ng HH, Kanagasundaram Y, Ng SB, Tam WL, Tenen DG, Chai L. Tan JL, et al. Among authors: tam wl. Gastroenterology. 2019 Dec;157(6):1615-1629.e17. doi: 10.1053/j.gastro.2019.08.022. Epub 2019 Aug 22. Gastroenterology. 2019. PMID: 31446059 Free PMC article.
102 results