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mRNA-LNP COVID-19 Vaccine Lipids Induce Complement Activation and Production of Proinflammatory Cytokines: Mechanisms, Effects of Complement Inhibitors, and Relevance to Adverse Reactions.
Bakos T, Mészáros T, Kozma GT, Berényi P, Facskó R, Farkas H, Dézsi L, Heirman C, de Koker S, Schiffelers R, Glatter KA, Radovits T, Szénási G, Szebeni J. Bakos T, et al. Among authors: szebeni j. Int J Mol Sci. 2024 Mar 22;25(7):3595. doi: 10.3390/ijms25073595. Int J Mol Sci. 2024. PMID: 38612407 Free PMC article.
Involvement of complement activation in the pulmonary vasoactivity of polystyrene nanoparticles in pigs: unique surface properties underlying alternative pathway activation and instant opsonization.
Mészáros T, Kozma GT, Shimizu T, Miyahara K, Turjeman K, Ishida T, Barenholz Y, Urbanics R, Szebeni J. Mészáros T, et al. Among authors: szebeni j. Int J Nanomedicine. 2018 Oct 11;13:6345-6357. doi: 10.2147/IJN.S161369. eCollection 2018. Int J Nanomedicine. 2018. PMID: 30349254 Free PMC article.
Pseudo-anaphylaxis to Polyethylene Glycol (PEG)-Coated Liposomes: Roles of Anti-PEG IgM and Complement Activation in a Porcine Model of Human Infusion Reactions.
Kozma GT, Mészáros T, Vashegyi I, Fülöp T, Örfi E, Dézsi L, Rosivall L, Bavli Y, Urbanics R, Mollnes TE, Barenholz Y, Szebeni J. Kozma GT, et al. Among authors: szebeni j. ACS Nano. 2019 Aug 27;13(8):9315-9324. doi: 10.1021/acsnano.9b03942. Epub 2019 Aug 6. ACS Nano. 2019. PMID: 31348638 Free article.
Mini-Factor H Modulates Complement-Dependent IL-6 and IL-10 Release in an Immune Cell Culture (PBMC) Model: Potential Benefits Against Cytokine Storm.
Kozma GT, Mészáros T, Bakos T, Hennies M, Bencze D, Uzonyi B, Győrffy B, Cedrone E, Dobrovolskaia MA, Józsi M, Szebeni J. Kozma GT, et al. Among authors: szebeni j. Front Immunol. 2021 Apr 28;12:642860. doi: 10.3389/fimmu.2021.642860. eCollection 2021. Front Immunol. 2021. PMID: 33995361 Free PMC article.
A naturally hypersensitive porcine model may help understand the mechanism of COVID-19 mRNA vaccine-induced rare (pseudo) allergic reactions: complement activation as a possible contributing factor.
Dézsi L, Mészáros T, Kozma G, H-Velkei M, Oláh CZ, Szabó M, Patkó Z, Fülöp T, Hennies M, Szebeni M, Barta BA, Merkely B, Radovits T, Szebeni J. Dézsi L, et al. Among authors: szebeni j, szebeni m. Geroscience. 2022 Apr;44(2):597-618. doi: 10.1007/s11357-021-00495-y. Epub 2022 Feb 11. Geroscience. 2022. PMID: 35146583 Free PMC article.
Complement-mediated hypersensitivity reactions to an amphotericin B-containing lipid complex (Abelcet) in pediatric patients and anesthetized rats: Benefits of slow infusion.
Milosevits G, Mészáros T, Őrfi E, Bakos T, Garami M, Kovács G, Dézsi L, Hamar P, Győrffy B, Szabó A, Szénási G, Szebeni J. Milosevits G, et al. Among authors: szebeni j. Nanomedicine. 2021 Jun;34:102366. doi: 10.1016/j.nano.2021.102366. Epub 2021 Feb 5. Nanomedicine. 2021. PMID: 33549818
141 results