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A targeted single mutation in influenza A virus universal epitope transforms immunogenicity and protective immunity via CD4+ T cell activation.
Hulin-Curtis S, Geary JK, MacLachlan BJ, Altmann DM, Baillon L, Cole DK, Greenshields-Watson A, Hesketh SJ, Humphreys IR, Jones IM, Lauder SN, Mason GH, Smart K, Scourfield DO, Scott J, Sukhova K, Stanton RJ, Wall A, Rizkallah PJ, Barclay WS, Gallimore A, Godkin A. Hulin-Curtis S, et al. Among authors: lauder sn. Cell Rep. 2024 May 30;43(6):114259. doi: 10.1016/j.celrep.2024.114259. Online ahead of print. Cell Rep. 2024. PMID: 38819988 Free article.
Acquisition of suppressive function by conventional T cells limits antitumor immunity upon Treg depletion.
Whiteside SK, Grant FM, Alvisi G, Clarke J, Tang L, Imianowski CJ, Zhang B, Evans AC, Wesolowski AJ, Conti AG, Yang J, Lauder SN, Clement M, Humphreys IR, Dooley J, Burton O, Liston A, Alloisio M, Voulaz E, Langhorne J, Okkenhaug K, Lugli E, Roychoudhuri R. Whiteside SK, et al. Among authors: lauder sn. Sci Immunol. 2023 Dec 15;8(90):eabo5558. doi: 10.1126/sciimmunol.abo5558. Epub 2023 Dec 15. Sci Immunol. 2023. PMID: 38100544 Free PMC article.
Three-dimensional Imaging Reveals Immune-driven Tumor-associated High Endothelial Venules as a Key Correlate of Tumor Rejection Following Depletion of Regulatory T Cells.
Milutinovic S, Abe J, Jones E, Kelch I, Smart K, Lauder SN, Somerville M, Ware C, Godkin A, Stein JV, Bogle G, Gallimore A. Milutinovic S, et al. Among authors: lauder sn. Cancer Res Commun. 2022 Dec 15;2(12):1641-1656. doi: 10.1158/2767-9764.CRC-21-0123. Cancer Res Commun. 2022. PMID: 36704666 Free PMC article.
PI3K Isoform Immunotherapy for Solid Tumours.
Scott J, Rees L, Gallimore A, Lauder SN. Scott J, et al. Among authors: lauder sn. Curr Top Microbiol Immunol. 2022;436:369-392. doi: 10.1007/978-3-031-06566-8_16. Curr Top Microbiol Immunol. 2022. PMID: 36243853 Review.
65 results