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FXR Agonism with Bile Acid Mimetic Reduces Pre-Clinical Triple-Negative Breast Cancer Burden.
Joseph SC, Eugin Simon S, Bohm MS, Kim M, Pye ME, Simmons BW, Graves DG, Thomas-Gooch SM, Tanveer UA, Holt JR, Ponnusamy S, Sipe LM, Hayes DN, Cook KL, Narayanan R, Pierre JF, Makowski L. Joseph SC, et al. Among authors: holt jr. Cancers (Basel). 2024 Mar 30;16(7):1368. doi: 10.3390/cancers16071368. Cancers (Basel). 2024. PMID: 38611046 Free PMC article.
Response to immune checkpoint blockade improved in pre-clinical model of breast cancer after bariatric surgery.
Sipe LM, Chaib M, Korba EB, Jo H, Lovely MC, Counts BR, Tanveer U, Holt JR, Clements JC, John NA, Daria D, Marion TN, Bohm MS, Sekhri R, Pingili AK, Teng B, Carson JA, Hayes DN, Davis MJ, Cook KL, Pierre JF, Makowski L. Sipe LM, et al. Among authors: holt jr. Elife. 2022 Jul 1;11:e79143. doi: 10.7554/eLife.79143. Elife. 2022. PMID: 35775614 Free PMC article.
Protein kinase C delta regulates mononuclear phagocytes and hinders response to immunotherapy in cancer.
Chaib M, Holt JR, Fisher EL, Sipe LM, Bohm MS, Joseph SC, Simmons BW, Eugin Simon S, Yarbro JR, Tanveer U, Halle JL, Carson JA, Hollingsworth TJ, Wei Q, Rathmell JC, Thomas PG, Hayes DN, Makowski L. Chaib M, et al. Among authors: holt jr. Sci Adv. 2023 Dec 22;9(51):eadd3231. doi: 10.1126/sciadv.add3231. Epub 2023 Dec 22. Sci Adv. 2023. PMID: 38134280 Free PMC article.
Identification of a targetable JAK-STAT enriched androgen receptor and androgen receptor splice variant positive triple-negative breast cancer subtype.
Asemota S, Effah W, Young KL, Holt J, Cripe L, Ponnusamy S, Thiyagarajan T, Hwang DJ, He Y, Mcnamara K, Johnson D, Wang Y, Grimes B, Khosrosereshki Y, Hollingsworth TJ, Fleming MD, Pritchard FE, Hendrix A, Khan F, Fan M, Makowski L, Yin Z, Sasano H, Hayes DN, Pfeffer LM, Miller DD, Narayanan R. Asemota S, et al. Cell Rep. 2023 Dec 26;42(12):113461. doi: 10.1016/j.celrep.2023.113461. Epub 2023 Nov 17. Cell Rep. 2023. PMID: 37979170 Free PMC article.
TP53, CDKN2A/P16, and NFE2L2/NRF2 regulate the incidence of pure- and combined-small cell lung cancer in mice.
Hamad SH, Montgomery SA, Simon JM, Bowman BM, Spainhower KB, Murphy RM, Knudsen ES, Fenton SE, Randell SH, Holt JR, Hayes DN, Witkiewicz AK, Oliver TG, Major MB, Weissman BE. Hamad SH, et al. Among authors: holt jr. Oncogene. 2022 Jun;41(25):3423-3432. doi: 10.1038/s41388-022-02348-0. Epub 2022 May 16. Oncogene. 2022. PMID: 35577980 Free PMC article.
Correction: TP53, CDKN2A/P16, and NFE2L2/NRF2 regulate the incidence of pure- and combined-small cell lung cancer in mice.
Hamad SH, Montgomery SA, Simon JM, Bowman BM, Spainhower KB, Murphy RM, Knudsen ES, Fenton SE, Randell SH, Holt JR, Hayes DN, Witkiewicz AK, Oliver TG, Major MB, Weissman BE. Hamad SH, et al. Among authors: holt jr. Oncogene. 2022 Sep;41(39):4485. doi: 10.1038/s41388-022-02442-3. Oncogene. 2022. PMID: 36002660 No abstract available.
322 results