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The autism susceptibility kinase, TAOK2, phosphorylates eEF2 and modulates translation.
Henis M, Rücker T, Scharrenberg R, Richter M, Baltussen L, Hong S, Meka DP, Schwanke B, Neelagandan N, Daaboul D, Murtaza N, Krisp C, Harder S, Schlüter H, Kneussel M, Hermans-Borgmeyer I, de Wit J, Singh KK, Duncan KE, de Anda FC. Henis M, et al. Among authors: duncan ke. Sci Adv. 2024 Apr 12;10(15):eadf7001. doi: 10.1126/sciadv.adf7001. Epub 2024 Apr 12. Sci Adv. 2024. PMID: 38608030 Free PMC article.
TDP-43 enhances translation of specific mRNAs linked to neurodegenerative disease.
Neelagandan N, Gonnella G, Dang S, Janiesch PC, Miller KK, Küchler K, Marques RF, Indenbirken D, Alawi M, Grundhoff A, Kurtz S, Duncan KE. Neelagandan N, et al. Among authors: duncan ke. Nucleic Acids Res. 2019 Jan 10;47(1):341-361. doi: 10.1093/nar/gky972. Nucleic Acids Res. 2019. PMID: 30357366 Free PMC article.
A novel mouse model for inhibition of DOHH-mediated hypusine modification reveals a crucial function in embryonic development, proliferation and oncogenic transformation.
Sievert H, Pällmann N, Miller KK, Hermans-Borgmeyer I, Venz S, Sendoel A, Preukschas M, Schweizer M, Boettcher S, Janiesch PC, Streichert T, Walther R, Hengartner MO, Manz MG, Brümmendorf TH, Bokemeyer C, Braig M, Hauber J, Duncan KE, Balabanov S. Sievert H, et al. Among authors: duncan ke. Dis Model Mech. 2014 Aug;7(8):963-76. doi: 10.1242/dmm.014449. Epub 2014 May 15. Dis Model Mech. 2014. PMID: 24832488 Free PMC article.
Impaired Amino Acid Transport at the Blood Brain Barrier Is a Cause of Autism Spectrum Disorder.
Tărlungeanu DC, Deliu E, Dotter CP, Kara M, Janiesch PC, Scalise M, Galluccio M, Tesulov M, Morelli E, Sonmez FM, Bilguvar K, Ohgaki R, Kanai Y, Johansen A, Esharif S, Ben-Omran T, Topcu M, Schlessinger A, Indiveri C, Duncan KE, Caglayan AO, Gunel M, Gleeson JG, Novarino G. Tărlungeanu DC, et al. Among authors: duncan ke. Cell. 2016 Dec 1;167(6):1481-1494.e18. doi: 10.1016/j.cell.2016.11.013. Cell. 2016. PMID: 27912058 Free PMC article.
101 results