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LDHB contributes to the regulation of lactate levels and basal insulin secretion in human pancreatic β cells.
Cuozzo F, Viloria K, Shilleh AH, Nasteska D, Frazer-Morris C, Tong J, Jiao Z, Boufersaoui A, Marzullo B, Rosoff DB, Smith HR, Bonner C, Kerr-Conte J, Pattou F, Nano R, Piemonti L, Johnson PRV, Spiers R, Roberts J, Lavery GG, Clark A, Ceresa CDL, Ray DW, Hodson L, Davies AP, Rutter GA, Oshima M, Scharfmann R, Merrins MJ, Akerman I, Tennant DA, Ludwig C, Hodson DJ. Cuozzo F, et al. Among authors: hodson dj. Cell Rep. 2024 Apr 23;43(4):114047. doi: 10.1016/j.celrep.2024.114047. Epub 2024 Apr 11. Cell Rep. 2024. PMID: 38607916 Free article.
Rfx6 maintains the functional identity of adult pancreatic β cells.
Piccand J, Strasser P, Hodson DJ, Meunier A, Ye T, Keime C, Birling MC, Rutter GA, Gradwohl G. Piccand J, et al. Among authors: hodson dj. Cell Rep. 2014 Dec 24;9(6):2219-32. doi: 10.1016/j.celrep.2014.11.033. Epub 2014 Dec 11. Cell Rep. 2014. PMID: 25497096 Free PMC article.
Glucocorticoids Reprogram β-Cell Signaling to Preserve Insulin Secretion.
Fine NHF, Doig CL, Elhassan YS, Vierra NC, Marchetti P, Bugliani M, Nano R, Piemonti L, Rutter GA, Jacobson DA, Lavery GG, Hodson DJ. Fine NHF, et al. Among authors: hodson dj. Diabetes. 2018 Feb;67(2):278-290. doi: 10.2337/db16-1356. Epub 2017 Dec 4. Diabetes. 2018. PMID: 29203512 Free PMC article.
Oncogenic IDH1 Mutations Promote Enhanced Proline Synthesis through PYCR1 to Support the Maintenance of Mitochondrial Redox Homeostasis.
Hollinshead KER, Munford H, Eales KL, Bardella C, Li C, Escribano-Gonzalez C, Thakker A, Nonnenmacher Y, Kluckova K, Jeeves M, Murren R, Cuozzo F, Ye D, Laurenti G, Zhu W, Hiller K, Hodson DJ, Hua W, Tomlinson IP, Ludwig C, Mao Y, Tennant DA. Hollinshead KER, et al. Among authors: hodson dj. Cell Rep. 2018 Mar 20;22(12):3107-3114. doi: 10.1016/j.celrep.2018.02.084. Cell Rep. 2018. PMID: 29562167 Free PMC article.
Vitamin-D-Binding Protein Contributes to the Maintenance of α Cell Function and Glucagon Secretion.
Viloria K, Nasteska D, Briant LJB, Heising S, Larner DP, Fine NHF, Ashford FB, da Silva Xavier G, Ramos MJ, Hasib A, Cuozzo F, Manning Fox JE, MacDonald PE, Akerman I, Lavery GG, Flaxman C, Morgan NG, Richardson SJ, Hewison M, Hodson DJ. Viloria K, et al. Among authors: hodson dj. Cell Rep. 2020 Jun 16;31(11):107761. doi: 10.1016/j.celrep.2020.107761. Cell Rep. 2020. PMID: 32553153 Free PMC article.
Proline synthesis through PYCR1 is required to support cancer cell proliferation and survival in oxygen-limiting conditions.
Westbrook RL, Bridges E, Roberts J, Escribano-Gonzalez C, Eales KL, Vettore LA, Walker PD, Vera-Siguenza E, Rana H, Cuozzo F, Eskla KL, Vellama H, Shaaban A, Nixon C, Luuk H, Lavery GG, Hodson DJ, Harris AL, Tennant DA. Westbrook RL, et al. Among authors: hodson dj. Cell Rep. 2022 Feb 1;38(5):110320. doi: 10.1016/j.celrep.2022.110320. Cell Rep. 2022. PMID: 35108535 Free PMC article.
174 results