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CRISPR editing to mimic porphyria combined with light: A new preclinical approach for prostate cancer.
Boutin J, Genevois C, Couillaud F, Lamrissi-Garcia I, Guyonnet-Duperat V, Bibeyran A, Lalanne M, Amintas S, Moranvillier I, Richard E, Blouin JM, Dabernat S, Moreau-Gaudry F, Bedel A. Boutin J, et al. Among authors: dabernat s. Mol Ther Oncol. 2024 Feb 8;32(1):200772. doi: 10.1016/j.omton.2024.200772. eCollection 2024 Mar 21. Mol Ther Oncol. 2024. PMID: 38596305 Free PMC article.
CRISPR-Cas9 genome editing induces megabase-scale chromosomal truncations.
Cullot G, Boutin J, Toutain J, Prat F, Pennamen P, Rooryck C, Teichmann M, Rousseau E, Lamrissi-Garcia I, Guyonnet-Duperat V, Bibeyran A, Lalanne M, Prouzet-Mauléon V, Turcq B, Ged C, Blouin JM, Richard E, Dabernat S, Moreau-Gaudry F, Bedel A. Cullot G, et al. Among authors: dabernat s. Nat Commun. 2019 Mar 8;10(1):1136. doi: 10.1038/s41467-019-09006-2. Nat Commun. 2019. PMID: 30850590 Free PMC article.
Mutation-Specific Guide RNA for Compound Heterozygous Porphyria On-target Scarless Correction by CRISPR/Cas9 in Stem Cells.
Prat F, Toutain J, Boutin J, Amintas S, Cullot G, Lalanne M, Lamrissi-Garcia I, Moranvillier I, Richard E, Blouin JM, Dabernat S, Moreau-Gaudry F, Bedel A. Prat F, et al. Among authors: dabernat s. Stem Cell Reports. 2020 Sep 8;15(3):677-693. doi: 10.1016/j.stemcr.2020.07.015. Epub 2020 Aug 13. Stem Cell Reports. 2020. PMID: 32795423 Free PMC article.
CRISPR-Cas9 globin editing can induce megabase-scale copy-neutral losses of heterozygosity in hematopoietic cells.
Boutin J, Rosier J, Cappellen D, Prat F, Toutain J, Pennamen P, Bouron J, Rooryck C, Merlio JP, Lamrissi-Garcia I, Cullot G, Amintas S, Guyonnet-Duperat V, Ged C, Blouin JM, Richard E, Dabernat S, Moreau-Gaudry F, Bedel A. Boutin J, et al. Among authors: dabernat s. Nat Commun. 2021 Aug 13;12(1):4922. doi: 10.1038/s41467-021-25190-6. Nat Commun. 2021. PMID: 34389729 Free PMC article.
Cell cycle arrest and p53 prevent ON-target megabase-scale rearrangements induced by CRISPR-Cas9.
Cullot G, Boutin J, Fayet S, Prat F, Rosier J, Cappellen D, Lamrissi I, Pennamen P, Bouron J, Amintas S, Thibault C, Moranvillier I, Laharanne E, Merlio JP, Guyonnet-Duperat V, Blouin JM, Richard E, Dabernat S, Moreau-Gaudry F, Bedel A. Cullot G, et al. Among authors: dabernat s. Nat Commun. 2023 Jul 10;14(1):4072. doi: 10.1038/s41467-023-39632-w. Nat Commun. 2023. PMID: 37429857 Free PMC article.
FGFR3 has tumor suppressor properties in cells with epithelial phenotype.
Lafitte M, Moranvillier I, Garcia S, Peuchant E, Iovanna J, Rousseau B, Dubus P, Guyonnet-Dupérat V, Belleannée G, Ramos J, Bedel A, de Verneuil H, Moreau-Gaudry F, Dabernat S. Lafitte M, et al. Among authors: dabernat s. Mol Cancer. 2013 Jul 31;12:83. doi: 10.1186/1476-4598-12-83. Mol Cancer. 2013. PMID: 23902722 Free PMC article.
52 results