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Structural analyses of the GI.4 norovirus by cryo-electron microscopy and X-ray crystallography revealing binding sites for human monoclonal antibodies.
Kimura-Someya T, Katsura K, Kato-Murayama M, Hosaka T, Uchikubo-Kamo T, Ihara K, Hanada K, Sato S, Murayama K, Kataoka M, Shirouzu M, Someya Y. Kimura-Someya T, et al. Among authors: hanada k. J Virol. 2024 May 14;98(5):e0019724. doi: 10.1128/jvi.00197-24. Epub 2024 Apr 9. J Virol. 2024. PMID: 38593321 Free PMC article.
Cryo-EM structure of the human ELMO1-DOCK5-Rac1 complex.
Kukimoto-Niino M, Katsura K, Kaushik R, Ehara H, Yokoyama T, Uchikubo-Kamo T, Nakagawa R, Mishima-Tsumagari C, Yonemochi M, Ikeda M, Hanada K, Zhang KYJ, Shirouzu M. Kukimoto-Niino M, et al. Among authors: hanada k. Sci Adv. 2021 Jul 21;7(30):eabg3147. doi: 10.1126/sciadv.abg3147. Print 2021 Jul. Sci Adv. 2021. PMID: 34290093 Free PMC article.
Potent SARS-CoV-2 neutralizing antibodies with therapeutic effects in two animal models.
Takeshita M, Fukuyama H, Kamada K, Matsumoto T, Makino-Okamura C, Uchikubo-Kamo T, Tomabechi Y, Hanada K, Moriyama S, Takahashi Y, Ishigaki H, Nakayama M, Nguyen CT, Kitagawa Y, Itoh Y, Imai M, Maemura T, Furusawa Y, Ueki H, Iwatsuki-Horimoto K, Ito M, Yamayoshi S, Kawaoka Y, Shirouzu M, Ishii M, Saya H, Kondo Y, Kaneko Y, Suzuki K, Fukunaga K, Takeuchi T. Takeshita M, et al. Among authors: hanada k. iScience. 2022 Dec 22;25(12):105596. doi: 10.1016/j.isci.2022.105596. Epub 2022 Nov 15. iScience. 2022. PMID: 36406861 Free PMC article.
Targeting Ras-binding domain of ELMO1 by computational nanobody design.
Tam C, Kukimoto-Niino M, Miyata-Yabuki Y, Tsuda K, Mishima-Tsumagari C, Ihara K, Inoue M, Yonemochi M, Hanada K, Matsumoto T, Shirouzu M, Zhang KYJ. Tam C, et al. Among authors: hanada k. Commun Biol. 2023 Mar 17;6(1):284. doi: 10.1038/s42003-023-04657-w. Commun Biol. 2023. PMID: 36932164 Free PMC article.
Potent neutralizing broad-spectrum antibody against SARS-CoV-2 generated from dual-antigen-specific B cells from convalescents.
Takeshita M, Fukuyama H, Kamada K, Matsumoto T, Makino-Okamura C, Lin Q, Sakuma M, Kawahara E, Yamazaki I, Uchikubo-Kamo T, Tomabechi Y, Hanada K, Hisano T, Moriyama S, Takahashi Y, Ito M, Imai M, Maemura T, Furusawa Y, Yamayoshi S, Kawaoka Y, Shirouzu M, Ishii M, Saya H, Kondo Y, Kaneko Y, Suzuki K, Fukunaga K, Takeuchi T; Keio Donner Project. Takeshita M, et al. Among authors: hanada k. iScience. 2023 Jun 16;26(6):106955. doi: 10.1016/j.isci.2023.106955. Epub 2023 May 25. iScience. 2023. PMID: 37288342 Free PMC article.
1,162 results