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Proapoptotic Bid is required for pulmonary fibrosis.
Budinger GR, Mutlu GM, Eisenbart J, Fuller AC, Bellmeyer AA, Baker CM, Wilson M, Ridge K, Barrett TA, Lee VY, Chandel NS. Budinger GR, et al. Proc Natl Acad Sci U S A. 2006 Mar 21;103(12):4604-9. doi: 10.1073/pnas.0507604103. Epub 2006 Mar 14. Proc Natl Acad Sci U S A. 2006. PMID: 16537427 Free PMC article.
Mitochondrial complex III-generated oxidants activate ASK1 and JNK to induce alveolar epithelial cell death following exposure to particulate matter air pollution.
Soberanes S, Urich D, Baker CM, Burgess Z, Chiarella SE, Bell EL, Ghio AJ, De Vizcaya-Ruiz A, Liu J, Ridge KM, Kamp DW, Chandel NS, Schumacker PT, Mutlu GM, Budinger GR. Soberanes S, et al. J Biol Chem. 2009 Jan 23;284(4):2176-86. doi: 10.1074/jbc.M808844200. Epub 2008 Nov 25. J Biol Chem. 2009. PMID: 19033436 Free PMC article.
HOIL-1L functions as the PKCζ ubiquitin ligase to promote lung tumor growth.
Queisser MA, Dada LA, Deiss-Yehiely N, Angulo M, Zhou G, Kouri FM, Knab LM, Liu J, Stegh AH, DeCamp MM, Budinger GR, Chandel NS, Ciechanover A, Iwai K, Sznajder JI. Queisser MA, et al. Am J Respir Crit Care Med. 2014 Sep 15;190(6):688-98. doi: 10.1164/rccm.201403-0463OC. Am J Respir Crit Care Med. 2014. PMID: 25118570 Free PMC article.
Lung-specific loss of α3 laminin worsens bleomycin-induced pulmonary fibrosis.
Morales-Nebreda LI, Rogel MR, Eisenberg JL, Hamill KJ, Soberanes S, Nigdelioglu R, Chi M, Cho T, Radigan KA, Ridge KM, Misharin AV, Woychek A, Hopkinson S, Perlman H, Mutlu GM, Pardo A, Selman M, Jones JC, Budinger GR. Morales-Nebreda LI, et al. Am J Respir Cell Mol Biol. 2015 Apr;52(4):503-12. doi: 10.1165/rcmb.2014-0057OC. Am J Respir Cell Mol Biol. 2015. PMID: 25188360 Free PMC article.
208 results