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A NAV2729-sensitive mechanism promotes adrenergic smooth muscle contraction and growth of stromal cells in the human prostate.
Yu Q, Gratzke C, Wang R, Li B, Kuppermann P, Herlemann A, Tamalunas A, Wang Y, Rutz B, Ciotkowska A, Wang X, Strittmatter F, Waidelich R, Stief CG, Hennenberg M. Yu Q, et al. Among authors: wang x, wang y, wang r. J Biol Chem. 2019 Aug 9;294(32):12231-12249. doi: 10.1074/jbc.RA119.007958. Epub 2019 Jun 26. J Biol Chem. 2019. PMID: 31243101 Free PMC article.
The STK16 inhibitor STK16-IN-1 inhibits non-adrenergic and non-neurogenic smooth muscle contractions in the human prostate and the human male detrusor.
Li B, Wang X, Rutz B, Wang R, Tamalunas A, Strittmatter F, Waidelich R, Stief CG, Hennenberg M. Li B, et al. Among authors: wang x, wang r. Naunyn Schmiedebergs Arch Pharmacol. 2020 May;393(5):829-842. doi: 10.1007/s00210-019-01797-x. Epub 2019 Dec 23. Naunyn Schmiedebergs Arch Pharmacol. 2020. PMID: 31867686
Onvansertib, a polo-like kinase 1 inhibitor, inhibits prostate stromal cell growth and prostate smooth muscle contraction, which is additive to inhibition by α1-blockers.
Wang X, Li B, Ciotkowska A, Rutz B, Erlander MG, Ridinger M, Wang R, Tamalunas A, Waidelich R, Stief CG, Hennenberg M. Wang X, et al. Among authors: wang r. Eur J Pharmacol. 2020 Apr 15;873:172985. doi: 10.1016/j.ejphar.2020.172985. Epub 2020 Feb 1. Eur J Pharmacol. 2020. PMID: 32017934
Inhibition of neurogenic and thromboxane A2 -induced human prostate smooth muscle contraction by the integrin α2β1 inhibitor BTT-3033 and the integrin-linked kinase inhibitor Cpd22.
Li B, Wang X, Wang R, Rutz B, Ciotkowska A, Gratzke C, Herlemann A, Spek A, Tamalunas A, Waidelich R, Stief CG, Hennenberg M. Li B, et al. Among authors: wang x, wang r. Prostate. 2020 Aug;80(11):831-849. doi: 10.1002/pros.23998. Epub 2020 May 25. Prostate. 2020. PMID: 32449814
Purinergic smooth muscle contractions in the human prostate: estimation of relevance and characterization of different agonists.
Spek A, Li B, Rutz B, Ciotkowska A, Huang R, Liu Y, Wang R, Strittmatter F, Waidelich R, Stief CG, Hennenberg M. Spek A, et al. Among authors: wang r. Naunyn Schmiedebergs Arch Pharmacol. 2021 Jun;394(6):1113-1131. doi: 10.1007/s00210-020-02044-4. Epub 2021 Jan 11. Naunyn Schmiedebergs Arch Pharmacol. 2021. PMID: 33427927 Free PMC article.
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