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Nucleic acid-based drugs for patients with solid tumours.
Huayamares SG, Loughrey D, Kim H, Dahlman JE, Sorscher EJ. Huayamares SG, et al. Among authors: sorscher ej. Nat Rev Clin Oncol. 2024 Jun;21(6):407-427. doi: 10.1038/s41571-024-00883-1. Epub 2024 Apr 8. Nat Rev Clin Oncol. 2024. PMID: 38589512 Review.
Engineered tRNAs suppress nonsense mutations in cells and in vivo.
Albers S, Allen EC, Bharti N, Davyt M, Joshi D, Perez-Garcia CG, Santos L, Mukthavaram R, Delgado-Toscano MA, Molina B, Kuakini K, Alayyoubi M, Park KJ, Acharya G, Gonzalez JA, Sagi A, Birket SE, Tearney GJ, Rowe SM, Manfredi C, Hong JS, Tachikawa K, Karmali P, Matsuda D, Sorscher EJ, Chivukula P, Ignatova Z. Albers S, et al. Among authors: sorscher ej. Nature. 2023 Jun;618(7966):842-848. doi: 10.1038/s41586-023-06133-1. Epub 2023 May 31. Nature. 2023. PMID: 37258671 Free PMC article.
Cystic fibrosis precision therapeutics: Emerging considerations.
Joshi D, Ehrhardt A, Hong JS, Sorscher EJ. Joshi D, et al. Among authors: sorscher ej. Pediatr Pulmonol. 2019 Nov;54 Suppl 3(Suppl 3):S13-S17. doi: 10.1002/ppul.24547. Pediatr Pulmonol. 2019. PMID: 31715091 Free PMC article. Review.
A small molecule that induces translational readthrough of CFTR nonsense mutations by eRF1 depletion.
Sharma J, Du M, Wong E, Mutyam V, Li Y, Chen J, Wangen J, Thrasher K, Fu L, Peng N, Tang L, Liu K, Mathew B, Bostwick RJ, Augelli-Szafran CE, Bihler H, Liang F, Mahiou J, Saltz J, Rab A, Hong J, Sorscher EJ, Mendenhall EM, Coppola CJ, Keeling KM, Green R, Mense M, Suto MJ, Rowe SM, Bedwell DM. Sharma J, et al. Among authors: sorscher ej. Nat Commun. 2021 Jul 16;12(1):4358. doi: 10.1038/s41467-021-24575-x. Nat Commun. 2021. PMID: 34272367 Free PMC article.
193 results