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Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.
Lü Y, Cho T, Mukherjee S, Suarez CF, Gonzalez-Foutel NS, Malik A, Martinez S, Dervovic D, Oh RH, Langille E, Al-Zahrani KN, Hoeg L, Lin ZY, Tsai R, Mbamalu G, Rotter V, Ashton-Prolla P, Moffat J, Chemes LB, Gingras AC, Oren M, Durocher D, Schramek D. Lü Y, et al. Among authors: oren m. Mol Syst Biol. 2024 Apr 5. doi: 10.1038/s44320-024-00032-x. Online ahead of print. Mol Syst Biol. 2024. PMID: 38580884 Free article.
Transcription regulation by mutant p53.
Weisz L, Oren M, Rotter V. Weisz L, et al. Among authors: oren m. Oncogene. 2007 Apr 2;26(15):2202-11. doi: 10.1038/sj.onc.1210294. Oncogene. 2007. PMID: 17401429 Review.
Mutant p53 gain-of-function in cancer.
Oren M, Rotter V. Oren M, et al. Cold Spring Harb Perspect Biol. 2010 Feb;2(2):a001107. doi: 10.1101/cshperspect.a001107. Cold Spring Harb Perspect Biol. 2010. PMID: 20182618 Free PMC article. Review.
Introduction: p53--the first twenty years.
Oren M, Rotter V. Oren M, et al. Cell Mol Life Sci. 1999 Jan;55(1):9-11. doi: 10.1007/s000180050265. Cell Mol Life Sci. 1999. PMID: 10065147 Review.
Targeting mutant p53 for cancer therapy.
Oren M, Tal P, Rotter V. Oren M, et al. Aging (Albany NY). 2016 Jun;8(6):1159-60. doi: 10.18632/aging.100992. Aging (Albany NY). 2016. PMID: 27347904 Free PMC article. No abstract available.
Cross-talk between mutant p53 and p62/SQSTM1 augments cancer cell migration by promoting the degradation of cell adhesion proteins.
Mukherjee S, Maddalena M, Lü Y, Martinez S, Nataraj NB, Noronha A, Sinha S, Teng K, Cohen-Kaplan V, Ziv T, Arandkar S, Hassin O, Chatterjee R, Pirona AC, Shreberk-Shaked M, Gershoni A, Aylon Y, Elazar Z, Yarden Y, Schramek D, Oren M. Mukherjee S, et al. Among authors: oren m. Proc Natl Acad Sci U S A. 2022 Apr 26;119(17):e2119644119. doi: 10.1073/pnas.2119644119. Epub 2022 Apr 19. Proc Natl Acad Sci U S A. 2022. PMID: 35439056 Free PMC article.
p53-Repressed miRNAs are involved with E2F in a feed-forward loop promoting proliferation.
Brosh R, Shalgi R, Liran A, Landan G, Korotayev K, Nguyen GH, Enerly E, Johnsen H, Buganim Y, Solomon H, Goldstein I, Madar S, Goldfinger N, Børresen-Dale AL, Ginsberg D, Harris CC, Pilpel Y, Oren M, Rotter V. Brosh R, et al. Among authors: oren m. Mol Syst Biol. 2008;4:229. doi: 10.1038/msb.2008.65. Epub 2008 Nov 25. Mol Syst Biol. 2008. PMID: 19034270 Free PMC article.
495 results