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E2F transcription factor-1 modulates expression of glutamine metabolic genes in mouse embryonic fibroblasts and uterine sarcoma cells.
Huber K, Giralt A, Dreos R, Michenthaler H, Geller S, Barquissau V, Ziegler DV, Tavernari D, Gallart-Ayala H, Krajina K, Jonas K, Ciriello G, Ivanisevic J, Prokesch A, Pichler M, Fajas L. Huber K, et al. Biochim Biophys Acta Mol Cell Res. 2024 Apr 3;1871(5):119721. doi: 10.1016/j.bbamcr.2024.119721. Online ahead of print. Biochim Biophys Acta Mol Cell Res. 2024. PMID: 38580088 Free article.
N-acetylaspartate pathway is nutrient responsive and coordinates lipid and energy metabolism in brown adipocytes.
Huber K, Hofer DC, Trefely S, Pelzmann HJ, Madreiter-Sokolowski C, Duta-Mare M, Schlager S, Trausinger G, Stryeck S, Graier WF, Kolb D, Magnes C, Snyder NW, Prokesch A, Kratky D, Madl T, Wellen KE, Bogner-Strauss JG. Huber K, et al. Biochim Biophys Acta Mol Cell Res. 2019 Mar;1866(3):337-348. doi: 10.1016/j.bbamcr.2018.08.017. Epub 2018 Aug 31. Biochim Biophys Acta Mol Cell Res. 2019. PMID: 30595160 Free PMC article.
Lysosomal acid lipase regulates fatty acid channeling in brown adipose tissue to maintain thermogenesis.
Duta-Mare M, Sachdev V, Leopold C, Kolb D, Vujic N, Korbelius M, Hofer DC, Xia W, Huber K, Auer M, Gottschalk B, Magnes C, Graier WF, Prokesch A, Radovic B, Bogner-Strauss JG, Kratky D. Duta-Mare M, et al. Among authors: huber k. Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Apr;1863(4):467-478. doi: 10.1016/j.bbalip.2018.01.011. Epub 2018 Jan 31. Biochim Biophys Acta Mol Cell Biol Lipids. 2018. PMID: 29374543 Free PMC article.
APMAP interacts with lysyl oxidase-like proteins, and disruption of Apmap leads to beneficial visceral adipose tissue expansion.
Pessentheiner AR, Huber K, Pelzmann HJ, Prokesch A, Radner FPW, Wolinski H, Lindroos-Christensen J, Hoefler G, Rülicke T, Birner-Gruenberger R, Bilban M, Bogner-Strauss JG. Pessentheiner AR, et al. Among authors: huber k. FASEB J. 2017 Sep;31(9):4088-4103. doi: 10.1096/fj.201601337R. Epub 2017 May 30. FASEB J. 2017. PMID: 28559441 Free PMC article.
Together, our data suggest that APMAP is a novel regulator of extracellular matrix components, and establish that APMAP is a potential target to mitigate obesity-associated insulin resistance.-Pessentheiner, A. R., Huber, K., Pelzmann, H. J., Prokesch, A., Radner, F …
Together, our data suggest that APMAP is a novel regulator of extracellular matrix components, and establish that APMAP is a potential targe …
Preoperative fibrinogen/CRP score predicts survival in upper urothelial tract carcinoma patients undergoing radical curative surgery.
Egger V, Hutterer GC, Mischinger J, Seles M, Pichler R, Mannweiler S, Huber K, Balihodzic A, Spiegelberg J, Bauernhofer T, Ahyai S, Zigeuner R, Pichler M, Barth DA. Egger V, et al. Among authors: huber k. World J Urol. 2023 May;41(5):1359-1364. doi: 10.1007/s00345-023-04379-y. Epub 2023 Apr 6. World J Urol. 2023. PMID: 37024555 Free PMC article.
N-acetylaspartate catabolism determines cytosolic acetyl-CoA levels and histone acetylation in brown adipocytes.
Prokesch A, Pelzmann HJ, Pessentheiner AR, Huber K, Madreiter-Sokolowski CT, Drougard A, Schittmayer M, Kolb D, Magnes C, Trausinger G, Graier WF, Birner-Gruenberger R, Pospisilik JA, Bogner-Strauss JG. Prokesch A, et al. Among authors: huber k. Sci Rep. 2016 Apr 5;6:23723. doi: 10.1038/srep23723. Sci Rep. 2016. PMID: 27045997 Free PMC article.
N-acetylaspartate availability is essential for juvenile survival on fat-free diet and determines metabolic health.
Hofer DC, Zirkovits G, Pelzmann HJ, Huber K, Pessentheiner AR, Xia W, Uno K, Miyazaki T, Kon K, Tsuneki H, Pendl T, Zoughbi WA, Madreiter-Sokolowski CT, Trausinger G, Abdellatif M, Schoiswohl G, Schreiber R, Eisenberg T, Magnes C, Sedej S, Eckhardt M, Sasahara M, Sasaoka T, Nitta A, Hoefler G, Graier WF, Kratky D, Auwerx J, Bogner-Strauss JG. Hofer DC, et al. Among authors: huber k. FASEB J. 2019 Dec;33(12):13808-13824. doi: 10.1096/fj.201801323R. Epub 2019 Nov 1. FASEB J. 2019. PMID: 31638418 Free PMC article.
Mechanistically, our data point to a possible role of NAA as modulator of pancreatic insulin secretion and suggest NAA as a critical energy metabolite for adipocyte and whole-body energy homeostasis.-Hofer, D. C., Zirkovits, G., Pelzmann, H. J., Huber, K., Pessenthe …
Mechanistically, our data point to a possible role of NAA as modulator of pancreatic insulin secretion and suggest NAA as a critical energy …
Quantitative subcellular acyl-CoA analysis reveals distinct nuclear metabolism and isoleucine-dependent histone propionylation.
Trefely S, Huber K, Liu J, Noji M, Stransky S, Singh J, Doan MT, Lovell CD, von Krusenstiern E, Jiang H, Bostwick A, Pepper HL, Izzo L, Zhao S, Xu JP, Bedi KC Jr, Rame JE, Bogner-Strauss JG, Mesaros C, Sidoli S, Wellen KE, Snyder NW. Trefely S, et al. Among authors: huber k. Mol Cell. 2022 Jan 20;82(2):447-462.e6. doi: 10.1016/j.molcel.2021.11.006. Epub 2021 Dec 1. Mol Cell. 2022. PMID: 34856123 Free PMC article.
2,039 results