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A brain-specific angiogenic mechanism enabled by tip cell specialization.
Schevenels G, Cabochette P, America M, Vandenborne A, De Grande L, Guenther S, He L, Dieu M, Christou B, Vermeersch M, Germano RFV, Perez-Morga D, Renard P, Martin M, Vanlandewijck M, Betsholtz C, Vanhollebeke B. Schevenels G, et al. Among authors: he l. Nature. 2024 Apr;628(8009):863-871. doi: 10.1038/s41586-024-07283-6. Epub 2024 Apr 3. Nature. 2024. PMID: 38570687 Free PMC article.
Pericytes regulate the blood-brain barrier.
Armulik A, Genové G, Mäe M, Nisancioglu MH, Wallgard E, Niaudet C, He L, Norlin J, Lindblom P, Strittmatter K, Johansson BR, Betsholtz C. Armulik A, et al. Among authors: he l. Nature. 2010 Nov 25;468(7323):557-61. doi: 10.1038/nature09522. Epub 2010 Oct 13. Nature. 2010. PMID: 20944627
Notch3 is necessary for blood vessel integrity in the central nervous system.
Henshall TL, Keller A, He L, Johansson BR, Wallgard E, Raschperger E, Mäe MA, Jin S, Betsholtz C, Lendahl U. Henshall TL, et al. Among authors: he l. Arterioscler Thromb Vasc Biol. 2015 Feb;35(2):409-20. doi: 10.1161/ATVBAHA.114.304849. Epub 2014 Dec 4. Arterioscler Thromb Vasc Biol. 2015. PMID: 25477343 Free article.
Gpr116 Receptor Regulates Distinctive Functions in Pneumocytes and Vascular Endothelium.
Niaudet C, Hofmann JJ, Mäe MA, Jung B, Gaengel K, Vanlandewijck M, Ekvärn E, Salvado MD, Mehlem A, Al Sayegh S, He L, Lebouvier T, Castro-Freire M, Katayama K, Hultenby K, Moessinger C, Tannenberg P, Cunha S, Pietras K, Laviña B, Hong J, Berg T, Betsholtz C. Niaudet C, et al. Among authors: he l. PLoS One. 2015 Sep 22;10(9):e0137949. doi: 10.1371/journal.pone.0137949. eCollection 2015. PLoS One. 2015. PMID: 26394398 Free PMC article.
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