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A brain-specific angiogenic mechanism enabled by tip cell specialization.
Schevenels G, Cabochette P, America M, Vandenborne A, De Grande L, Guenther S, He L, Dieu M, Christou B, Vermeersch M, Germano RFV, Perez-Morga D, Renard P, Martin M, Vanlandewijck M, Betsholtz C, Vanhollebeke B. Schevenels G, et al. Among authors: guenther s. Nature. 2024 Apr;628(8009):863-871. doi: 10.1038/s41586-024-07283-6. Epub 2024 Apr 3. Nature. 2024. PMID: 38570687 Free PMC article.
The potassium channel KCNJ13 is essential for smooth muscle cytoskeletal organization during mouse tracheal tubulogenesis.
Yin W, Kim HT, Wang S, Gunawan F, Wang L, Kishimoto K, Zhong H, Roman D, Preussner J, Guenther S, Graef V, Buettner C, Grohmann B, Looso M, Morimoto M, Mardon G, Offermanns S, Stainier DYR. Yin W, et al. Among authors: guenther s. Nat Commun. 2018 Jul 19;9(1):2815. doi: 10.1038/s41467-018-05043-5. Nat Commun. 2018. PMID: 30022023 Free PMC article.
Myh10 deficiency leads to defective extracellular matrix remodeling and pulmonary disease.
Kim HT, Yin W, Jin YJ, Panza P, Gunawan F, Grohmann B, Buettner C, Sokol AM, Preussner J, Guenther S, Kostin S, Ruppert C, Bhagwat AM, Ma X, Graumann J, Looso M, Guenther A, Adelstein RS, Offermanns S, Stainier DYR. Kim HT, et al. Among authors: guenther s, guenther a. Nat Commun. 2018 Nov 2;9(1):4600. doi: 10.1038/s41467-018-06833-7. Nat Commun. 2018. PMID: 30389913 Free PMC article.
A YAP/TAZ-TEAD signalling module links endothelial nutrient acquisition to angiogenic growth.
Ong YT, Andrade J, Armbruster M, Shi C, Castro M, Costa ASH, Sugino T, Eelen G, Zimmermann B, Wilhelm K, Lim J, Watanabe S, Guenther S, Schneider A, Zanconato F, Kaulich M, Pan D, Braun T, Gerhardt H, Efeyan A, Carmeliet P, Piccolo S, Grosso AR, Potente M. Ong YT, et al. Among authors: guenther s. Nat Metab. 2022 Jun;4(6):672-682. doi: 10.1038/s42255-022-00584-y. Epub 2022 Jun 20. Nat Metab. 2022. PMID: 35726026 Free PMC article.
Zeb1-Hdac2-eNOS circuitry identifies early cardiovascular precursors in naive mouse embryonic stem cells.
Cencioni C, Spallotta F, Savoia M, Kuenne C, Guenther S, Re A, Wingert S, Rehage M, Sürün D, Siragusa M, Smith JG, Schnütgen F, von Melchner H, Rieger MA, Martelli F, Riccio A, Fleming I, Braun T, Zeiher AM, Farsetti A, Gaetano C. Cencioni C, et al. Among authors: guenther s. Nat Commun. 2018 Mar 29;9(1):1281. doi: 10.1038/s41467-018-03668-0. Nat Commun. 2018. PMID: 29599503 Free PMC article.
281 results