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Glioblastoma-instructed microglia transition to heterogeneous phenotypic states with phagocytic and dendritic cell-like features in patient tumors and patient-derived orthotopic xenografts.
Yabo YA, Moreno-Sanchez PM, Pires-Afonso Y, Kaoma T, Nosirov B, Scafidi A, Ermini L, Lipsa A, Oudin A, Kyriakis D, Grzyb K, Poovathingal SK, Poli A, Muller A, Toth R, Klink B, Berchem G, Berthold C, Hertel F, Mittelbronn M, Heiland DH, Skupin A, Nazarov PV, Niclou SP, Michelucci A, Golebiewska A. Yabo YA, et al. Among authors: mittelbronn m. Genome Med. 2024 Apr 2;16(1):51. doi: 10.1186/s13073-024-01321-8. Genome Med. 2024. PMID: 38566128 Free PMC article.
Actin cytoskeleton depolymerization increases matrix metalloproteinase gene expression in breast cancer cells by promoting translocation of cysteine-rich protein 2 to the nucleus.
Mgrditchian T, Brown-Clay J, Hoffmann C, Müller T, Filali L, Ockfen E, Mao X, Moreau F, Casellas CP, Kaoma T, Mittelbronn M, Thomas C. Mgrditchian T, et al. Among authors: mittelbronn m. Front Cell Dev Biol. 2023 May 15;11:1100938. doi: 10.3389/fcell.2023.1100938. eCollection 2023. Front Cell Dev Biol. 2023. PMID: 37266453 Free PMC article.
Single-cell transcriptomics of NRAS-mutated melanoma transitioning to drug resistance reveals P2RX7 as an indicator of early drug response.
Randic T, Magni S, Philippidou D, Margue C, Grzyb K, Preis JR, Wroblewska JP, Nazarov PV, Mittelbronn M, Frauenknecht KBM, Skupin A, Kreis S. Randic T, et al. Among authors: mittelbronn m. Cell Rep. 2023 Jul 25;42(7):112696. doi: 10.1016/j.celrep.2023.112696. Epub 2023 Jun 29. Cell Rep. 2023. PMID: 37379213 Free article.
Blocking TGF-β- and Epithelial-to-Mesenchymal Transition (EMT)-mediated activation of vessel-associated mural cells in glioblastoma impacts tumor angiogenesis.
Merk L, Regel K, Eckhardt H, Evers M, El-Ayoubi A, Mittelbronn M, Krüger M, Gérardy JJ, Mack AF, Naumann U. Merk L, et al. Among authors: mittelbronn m. Free Neuropathol. 2024 Mar 1;5:5-4. doi: 10.17879/freeneuropathology-2024-5188. eCollection 2024 Jan. Free Neuropathol. 2024. PMID: 38455669 Free PMC article.
TGF-Beta Modulates the Integrity of the Blood Brain Barrier In Vitro, and Is Associated with Metabolic Alterations in Pericytes.
Schumacher L, Slimani R, Zizmare L, Ehlers J, Kleine Borgmann F, Fitzgerald JC, Fallier-Becker P, Beckmann A, Grißmer A, Meier C, El-Ayoubi A, Devraj K, Mittelbronn M, Trautwein C, Naumann U. Schumacher L, et al. Among authors: mittelbronn m. Biomedicines. 2023 Jan 14;11(1):214. doi: 10.3390/biomedicines11010214. Biomedicines. 2023. PMID: 36672722 Free PMC article.
337 results