Prakash A - Search Results

1

Multitarget action of Benzothiazole-piperazine small hybrid molecule against Alzheimer's disease: In silico, In vitro, and In vivo investigation.

Mishra CB, Shalini S, Gusain S, Kumar P, Kumari S, Choi YS, Kumari J, Moku BK, Yadav AK, Prakash A, Jeon R, Tiwari M. Mishra CB, et al. Among authors: prakash a. Biomed Pharmacother. 2024 May;174:116484. doi: 10.1016/j.biopha.2024.116484. Epub 2024 Apr 1. Biomed Pharmacother. 2024. PMID: 38565058 Free article.

2

Development of novel carbazole derivatives with effective multifunctional action against Alzheimer's diseases: Design, synthesis, in silico, in vitro and in vivo investigation.

Mishra CB, Gusain S, Shalini S, Kumari S, Prakash A, Kumari N, Yadav AK, Kumari J, Kumar K, Tiwari M. Mishra CB, et al. Among authors: prakash a. Bioorg Chem. 2020 Jan;95:103524. doi: 10.1016/j.bioorg.2019.103524. Epub 2019 Dec 28. Bioorg Chem. 2020. PMID: 31918396

3

Design, synthesis, in-silico and biological evaluation of novel donepezil derivatives as multi-target-directed ligands for the treatment of Alzheimer's disease.

Mishra CB, Kumari S, Manral A, Prakash A, Saini V, Lynn AM, Tiwari M. Mishra CB, et al. Among authors: prakash a. Eur J Med Chem. 2017 Jan 5;125:736-750. doi: 10.1016/j.ejmech.2016.09.057. Epub 2016 Sep 19. Eur J Med Chem. 2017. PMID: 27721157

4

Discovery of novel Methylsulfonyl phenyl derivatives as potent human Cyclooxygenase-2 inhibitors with effective anticonvulsant action: Design, synthesis, in-silico, in-vitro and in-vivo evaluation.

Mishra CB, Kumari S, Prakash A, Yadav R, Tiwari AK, Pandey P, Tiwari M. Mishra CB, et al. Among authors: prakash a. Eur J Med Chem. 2018 May 10;151:520-532. doi: 10.1016/j.ejmech.2018.04.007. Epub 2018 Apr 4. Eur J Med Chem. 2018. PMID: 29655084

5

Novel Carbazole-Piperazine Hybrid Small Molecule Induces Apoptosis by Targeting BCL-2 and Inhibits Tumor Progression in Lung Adenocarcinoma in Vitro and Xenograft Mice Model.

Mongre RK, Mishra CB, Prakash A, Jung S, Lee BS, Kumari S, Hong JT, Lee MS. Mongre RK, et al. Among authors: prakash a. Cancers (Basel). 2019 Aug 25;11(9):1245. doi: 10.3390/cancers11091245. Cancers (Basel). 2019. PMID: 31450709 Free PMC article.

6

Development of novel N-(6-methanesulfonyl-benzothiazol-2-yl)-3-(4-substituted-piperazin-1-yl)-propionamides with cholinesterase inhibition, anti-β-amyloid aggregation, neuroprotection and cognition enhancing properties for the therapy of Alzheimer's disease.

Mishra CB, Shalini S, Gusain S, Prakash A, Kumari J, Kumari S, Yadav AK, Lynn AM, Tiwari M. Mishra CB, et al. Among authors: prakash a. RSC Adv. 2020 May 5;10(30):17602-17619. doi: 10.1039/d0ra00663g. eCollection 2020 May 5. RSC Adv. 2020. PMID: 35515597 Free PMC article.

7

Design and synthesis of a novel class of carbonic anhydrase-IX inhibitor 1-(3-(phenyl/4-fluorophenyl)-7-imino-3H-[1,2,3]triazolo[4,5d]pyrimidin 6(7H)yl)urea.

Kumari S, Idrees D, Mishra CB, Prakash A, Wahiduzzaman, Ahmad F, Hassan MI, Tiwari M. Kumari S, et al. Among authors: prakash a. J Mol Graph Model. 2016 Mar;64:101-109. doi: 10.1016/j.jmgm.2016.01.006. Epub 2016 Jan 21. J Mol Graph Model. 2016. PMID: 26826799

8

Design, synthesis, in silico and biological evaluation of novel 2-(4-(4-substituted piperazin-1-yl)benzylidene)hydrazine carboxamides.

Kumari S, Mishra CB, Idrees D, Prakash A, Yadav R, Hassan MI, Tiwari M. Kumari S, et al. Among authors: prakash a. Mol Divers. 2017 Feb;21(1):163-174. doi: 10.1007/s11030-016-9714-7. Epub 2016 Dec 30. Mol Divers. 2017. PMID: 28039637

9

Identifying the natural polyphenol catechin as a multi-targeted agent against SARS-CoV-2 for the plausible therapy of COVID-19: an integrated computational approach.

Mishra CB, Pandey P, Sharma RD, Malik MZ, Mongre RK, Lynn AM, Prasad R, Jeon R, Prakash A. Mishra CB, et al. Among authors: prakash a. Brief Bioinform. 2021 Mar 22;22(2):1346-1360. doi: 10.1093/bib/bbaa378. Brief Bioinform. 2021. PMID: 33386025 Free PMC article.

10

Anti-breast cancer action of carbonic anhydrase IX inhibitor 4-[4-(4-Benzo[1,3]dioxol-5-ylmethyl-piperazin-1-yl)-benzylidene-hydrazinocarbonyl]-benzenesulfonamide (BSM-0004): in vitro and in vivo studies.

Mishra CB, Mongre RK, Prakash A, Jeon R, Supuran CT, Lee MS. Mishra CB, et al. Among authors: prakash a. J Enzyme Inhib Med Chem. 2021 Dec;36(1):954-963. doi: 10.1080/14756366.2021.1909580. J Enzyme Inhib Med Chem. 2021. PMID: 33947294 Free PMC article.

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