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CRISPR-Cas9-assisted genome editing in E. coli elevates the frequency of unintended mutations.
bioRxiv [Preprint]. 2024 Mar 19:2024.03.19.584922. doi: 10.1101/2024.03.19.584922.
bioRxiv. 2024.
PMID: 38562785
Free PMC article.
Preprint.
Synonymous edits in the Escherichia coli genome have substantial and condition-dependent effects on fitness.
Yang DD, Rusch LM, Widney KA, Morgenthaler AB, Copley SD.
Yang DD, et al. Among authors: widney ka.
Proc Natl Acad Sci U S A. 2024 Jan 30;121(5):e2316834121. doi: 10.1073/pnas.2316834121. Epub 2024 Jan 22.
Proc Natl Acad Sci U S A. 2024.
PMID: 38252823
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How to Recruit a Promiscuous Enzyme to Serve a New Function.
Copley SD, Newton MS, Widney KA.
Copley SD, et al. Among authors: widney ka.
Biochemistry. 2023 Jan 17;62(2):300-308. doi: 10.1021/acs.biochem.2c00249. Epub 2022 Jun 21.
Biochemistry. 2023.
PMID: 35729117
Free PMC article.
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Determinants of sulphur chemolithoautotrophy in the extremely thermoacidophilic Sulfolobales.
Zeldes BM, Loder AJ, Counts JA, Haque M, Widney KA, Keller LM, Albers SV, Kelly RM.
Zeldes BM, et al. Among authors: widney ka.
Environ Microbiol. 2019 Oct;21(10):3696-3710. doi: 10.1111/1462-2920.14712. Epub 2019 Jul 9.
Environ Microbiol. 2019.
PMID: 31188531
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