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MLH1 deficiency leads to deregulated mitochondrial metabolism.
Rashid S, Freitas MO, Cucchi D, Bridge G, Yao Z, Gay L, Williams M, Wang J, Suraweera N, Silver A, McDonald SAC, Chelala C, Szabadkai G, Martin SA. Rashid S, et al. Among authors: suraweera n. Cell Death Dis. 2019 Oct 22;10(11):795. doi: 10.1038/s41419-019-2018-y. Cell Death Dis. 2019. PMID: 31641109 Free PMC article.
Remodelling of microRNAs in colorectal cancer by hypoxia alters metabolism profiles and 5-fluorouracil resistance.
Nijhuis A, Thompson H, Adam J, Parker A, Gammon L, Lewis A, Bundy JG, Soga T, Jalaly A, Propper D, Jeffery R, Suraweera N, McDonald S, Thaha MA, Feakins R, Lowe R, Bishop CL, Silver A. Nijhuis A, et al. Among authors: suraweera n. Hum Mol Genet. 2017 Apr 15;26(8):1552-1564. doi: 10.1093/hmg/ddx059. Hum Mol Genet. 2017. PMID: 28207045 Free PMC article.
Relative telomere lengths in tumor and normal mucosa are related to disease progression and chromosome instability profiles in colorectal cancer.
Suraweera N, Mouradov D, Li S, Jorissen RN, Hampson D, Ghosh A, Sengupta N, Thaha M, Ahmed S, Kirwan M, Aleva F, Propper D, Feakins RM, Vulliamy T, Elwood NJ, Tian P, Ward RL, Hawkins NJ, Xu ZZ, Molloy PL, Jones IT, Croxford M, Gibbs P, Silver A, Sieber OM. Suraweera N, et al. Oncotarget. 2016 Jun 14;7(24):36474-36488. doi: 10.18632/oncotarget.9015. Oncotarget. 2016. PMID: 27167335 Free PMC article.
DUOX2 and DUOXA2 form the predominant enzyme system capable of producing the reactive oxygen species H2O2 in active ulcerative colitis and are modulated by 5-aminosalicylic acid.
MacFie TS, Poulsom R, Parker A, Warnes G, Boitsova T, Nijhuis A, Suraweera N, Poehlmann A, Szary J, Feakins R, Jeffery R, Harper RW, Jubb AM, Lindsay JO, Silver A. MacFie TS, et al. Among authors: suraweera n. Inflamm Bowel Dis. 2014 Mar;20(3):514-24. doi: 10.1097/01.MIB.0000442012.45038.0e. Inflamm Bowel Dis. 2014. PMID: 24492313
Analysis of colorectal cancers in British Bangladeshi identifies early onset, frequent mucinous histotype and a high prevalence of RBFOX1 deletion.
Sengupta N, Yau C, Sakthianandeswaren A, Mouradov D, Gibbs P, Suraweera N, Cazier JB, Polanco-Echeverry G, Ghosh A, Thaha M, Ahmed S, Feakins R, Propper D, Dorudi S, Sieber O, Silver A, Lai C. Sengupta N, et al. Among authors: suraweera n. Mol Cancer. 2013 Jan 3;12:1. doi: 10.1186/1476-4598-12-1. Mol Cancer. 2013. PMID: 23286373 Free PMC article.
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