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Ruxolitinib: A new hope for ventilator-induced diaphragm dysfunction.
Addinsall AB, Cacciani N, Moruzzi N, Akkad H, Maestri A, Berggren PO, Widegren A, Bergquist J, Tchkonia T, Kirkland JL, Larsson L. Addinsall AB, et al. Among authors: kirkland jl. Acta Physiol (Oxf). 2024 May;240(5):e14128. doi: 10.1111/apha.14128. Epub 2024 Mar 29. Acta Physiol (Oxf). 2024. PMID: 38551103
Local senolysis in aged mice only partially replicates the benefits of systemic senolysis.
Farr JN, Saul D, Doolittle ML, Kaur J, Rowsey JL, Vos SJ, Froemming MN, Lagnado AB, Zhu Y, Weivoda M, Ikeno Y, Pignolo RJ, Niedernhofer LJ, Robbins PD, Jurk D, Passos JF, LeBrasseur NK, Tchkonia T, Kirkland JL, Monroe DG, Khosla S. Farr JN, et al. Among authors: kirkland jl. J Clin Invest. 2023 Apr 17;133(8):e162519. doi: 10.1172/JCI162519. J Clin Invest. 2023. PMID: 36809340 Free PMC article.
Cellular senescence in skin-related research: Targeted signaling pathways and naturally occurring therapeutic agents.
Dańczak-Pazdrowska A, Gornowicz-Porowska J, Polańska A, Krajka-Kuźniak V, Stawny M, Gostyńska A, Rubiś B, Nourredine S, Ashiqueali S, Schneider A, Tchkonia T, Wyles SP, Kirkland JL, Masternak MM. Dańczak-Pazdrowska A, et al. Among authors: kirkland jl. Aging Cell. 2023 Jun;22(6):e13845. doi: 10.1111/acel.13845. Epub 2023 Apr 11. Aging Cell. 2023. PMID: 37042069 Free PMC article. Review.
Interleukin-6 in Patients With Heart Failure and Preserved Ejection Fraction.
Alogna A, Koepp KE, Sabbah M, Espindola Netto JM, Jensen MD, Kirkland JL, Lam CSP, Obokata M, Petrie MC, Ridker PM, Sorimachi H, Tchkonia T, Voors A, Redfield MM, Borlaug BA. Alogna A, et al. Among authors: kirkland jl. JACC Heart Fail. 2023 Nov;11(11):1549-1561. doi: 10.1016/j.jchf.2023.06.031. Epub 2023 Aug 9. JACC Heart Fail. 2023. PMID: 37565977 Free PMC article.
Caloric Restriction Intervention Alters Specific Circulating Biomarkers of the Senescence-Associated Secretome in Middle-Aged and Older Adults With Obesity and Prediabetes in an 18-Week Randomized Controlled Trial.
Justice JN, Leng XI, LeBrasseur NK, Tchkonia T, Kirkland JL, Mitin N, Liu Y, Kritchevsky SB, Nicklas BJ, Ding J. Justice JN, et al. Among authors: kirkland jl. J Gerontol A Biol Sci Med Sci. 2024 Jan 1;79(1):glad214. doi: 10.1093/gerona/glad214. J Gerontol A Biol Sci Med Sci. 2024. PMID: 37738560 Clinical Trial.
Clinical validation of C12FDG as a marker associated with senescence and osteoarthritic phenotypes.
Hambright WS, Duke VR, Goff AD, Goff AW, Minas LT, Kloser H, Gao X, Huard C, Guo P, Lu A, Mitchell J, Mullen M, Su C, Tchkonia T, Espindola Netto JM, Robbins PD, Niedernhofer LJ, Kirkland JL, Bahney CS, Philippon M, Huard J. Hambright WS, et al. Among authors: kirkland jl. Aging Cell. 2024 May;23(5):e14113. doi: 10.1111/acel.14113. Epub 2024 May 6. Aging Cell. 2024. PMID: 38708778 Free PMC article.
353 results