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Role of KCNK3 Dysfunction in Dasatinib-associated PAH and Endothelial Cell Dysfunction.
Le Ribeuz H, Saint-Martin Willer A, Chevalier B, Sancho M, Masson B, Eyries M, Jung V, Guerrera IC, Dutheil M, El Jekmek K, Laubry L, Carpentier G, Perez-Vizcaino F, Tu L, Guignabert C, Chaumais MC, Péchoux C, Humbert M, Hinzpeter A, Mercier O, Capuano V, Montani D, Antigny F. Le Ribeuz H, et al. Among authors: humbert m. Am J Respir Cell Mol Biol. 2024 Mar 28. doi: 10.1165/rcmb.2023-0185OC. Online ahead of print. Am J Respir Cell Mol Biol. 2024. PMID: 38546978
SUR1 As a New Therapeutic Target for Pulmonary Arterial Hypertension.
Le Ribeuz H, Masson B, Capuano V, Dutheil M, Gooroochurn H, Boët A, Ghigna MR, De Montpreville V, Girerd B, Lambert M, Mercier O, Chung WK, Humbert M, Montani D, Antigny F. Le Ribeuz H, et al. Among authors: humbert m. Am J Respir Cell Mol Biol. 2022 May;66(5):539-554. doi: 10.1165/rcmb.2021-0180OC. Am J Respir Cell Mol Biol. 2022. PMID: 35175177
A critical role for p130Cas in the progression of pulmonary hypertension in humans and rodents.
Tu L, De Man FS, Girerd B, Huertas A, Chaumais MC, Lecerf F, François C, Perros F, Dorfmüller P, Fadel E, Montani D, Eddahibi S, Humbert M, Guignabert C. Tu L, et al. Among authors: humbert m. Am J Respir Crit Care Med. 2012 Oct 1;186(7):666-76. doi: 10.1164/rccm.201202-0309OC. Epub 2012 Jul 12. Am J Respir Crit Care Med. 2012. PMID: 22798315 Free PMC article.
KCNK3: new gene target for pulmonary hypertension?
Girerd B, Perros F, Antigny F, Humbert M, Montani D. Girerd B, et al. Among authors: humbert m. Expert Rev Respir Med. 2014 Aug;8(4):385-7. doi: 10.1586/17476348.2014.909731. Epub 2014 Apr 18. Expert Rev Respir Med. 2014. PMID: 24742047
Dasatinib increases endothelial permeability leading to pleural effusion.
Phan C, Jutant EM, Tu L, Thuillet R, Seferian A, Montani D, Huertas A, Bezu JV, Breijer F, Vonk Noordegraaf A, Humbert M, Aman J, Guignabert C. Phan C, et al. Among authors: humbert m. Eur Respir J. 2018 Jan 18;51(1):1701096. doi: 10.1183/13993003.01096-2017. Print 2018 Jan. Eur Respir J. 2018. PMID: 29348177 Free article.
Loss of KCNK3 is a hallmark of RV hypertrophy/dysfunction associated with pulmonary hypertension.
Lambert M, Boet A, Rucker-Martin C, Mendes-Ferreira P, Capuano V, Hatem S, Adão R, Brás-Silva C, Hautefort A, Michel JB, Dorfmuller P, Fadel E, Kotsimbos T, Price L, Jourdon P, Montani D, Humbert M, Perros F, Antigny F. Lambert M, et al. Among authors: humbert m. Cardiovasc Res. 2018 May 1;114(6):880-893. doi: 10.1093/cvr/cvy016. Cardiovasc Res. 2018. PMID: 29360952
1,370 results