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Trans-amplifying RNA expressing functional miRNA mediates target gene suppression and simultaneous transgene expression.
Yıldız A, Hasani A, Hempel T, Köhl N, Beicht A, Becker R, Hubich-Rau S, Suchan M, Poleganov MA, Sahin U, Beissert T. Yıldız A, et al. Among authors: poleganov ma. Mol Ther Nucleic Acids. 2024 Mar 5;35(2):102162. doi: 10.1016/j.omtn.2024.102162. eCollection 2024 Jun 11. Mol Ther Nucleic Acids. 2024. PMID: 38545619 Free PMC article.
Improving mRNA-Based Therapeutic Gene Delivery by Expression-Augmenting 3' UTRs Identified by Cellular Library Screening.
Orlandini von Niessen AG, Poleganov MA, Rechner C, Plaschke A, Kranz LM, Fesser S, Diken M, Löwer M, Vallazza B, Beissert T, Bukur V, Kuhn AN, Türeci Ö, Sahin U. Orlandini von Niessen AG, et al. Among authors: poleganov ma. Mol Ther. 2019 Apr 10;27(4):824-836. doi: 10.1016/j.ymthe.2018.12.011. Epub 2018 Dec 18. Mol Ther. 2019. PMID: 30638957 Free PMC article.