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Page 1
Extracellular Vesicle-Encapsulated Adeno-Associated Viruses for Therapeutic Gene Delivery to the Heart.
Li X, La Salvia S, Liang Y, Adamiak M, Kohlbrenner E, Jeong D, Chepurko E, Ceholski D, Lopez-Gordo E, Yoon S, Mathiyalagan P, Agarwal N, Jha D, Lodha S, Daaboul G, Phan A, Raisinghani N, Zhang S, Zangi L, Gonzalez-Kozlova E, Dubois N, Dogra N, Hajjar RJ, Sahoo S. Li X, et al. Among authors: kohlbrenner e. Circulation. 2023 Aug;148(5):405-425. doi: 10.1161/CIRCULATIONAHA.122.063759. Epub 2023 Jul 6. Circulation. 2023. PMID: 37409482 Free article.
Gene editing reverses arrhythmia susceptibility in humanized PLN-R14del mice: modelling a European cardiomyopathy with global impact.
Dave J, Raad N, Mittal N, Zhang L, Fargnoli A, Oh JG, Savoia ME, Hansen J, Fava M, Yin X, Theofilatos K, Ceholski D, Kohlbrenner E, Jeong D, Wills L, Nonnenmacher M, Haghighi K, Costa KD, Turnbull IC, Mayr M, Cai CL, Kranias EG, Akar FG, Hajjar RJ, Stillitano F. Dave J, et al. Among authors: kohlbrenner e. Cardiovasc Res. 2022 Dec 9;118(15):3140-3150. doi: 10.1093/cvr/cvac021. Cardiovasc Res. 2022. PMID: 35191471 Free PMC article.
Genomic attributes of homology-directed DNA repair deficiency in metastatic prostate cancer.
De Sarkar N, Dasgupta S, Chatterjee P, Coleman I, Ha G, Ang LS, Kohlbrenner EA, Frank SB, Nunez TA, Salipante SJ, Corey E, Morrissey C, Van Allen E, Schweizer MT, Haffner MC, Patel R, Hanratty B, Lucas JM, Dumpit RF, Pritchard CC, Montgomery RB, Nelson PS. De Sarkar N, et al. Among authors: kohlbrenner ea. JCI Insight. 2021 Dec 8;6(23):e152789. doi: 10.1172/jci.insight.152789. JCI Insight. 2021. PMID: 34877933 Free PMC article.
Combination Therapy with STAT3 Inhibitor Enhances SERCA2a-Induced BMPR2 Expression and Inhibits Pulmonary Arterial Hypertension.
Bisserier M, Katz MG, Bueno-Beti C, Brojakowska A, Zhang S, Gubara S, Kohlbrenner E, Fazal S, Fargnoli A, Dorfmuller P, Humbert M, Hata A, Goukassian DA, Sassi Y, Hadri L. Bisserier M, et al. Among authors: kohlbrenner e. Int J Mol Sci. 2021 Aug 24;22(17):9105. doi: 10.3390/ijms22179105. Int J Mol Sci. 2021. PMID: 34502015 Free PMC article.
Arrhythmia Mechanism and Dynamics in a Humanized Mouse Model of Inherited Cardiomyopathy Caused by Phospholamban R14del Mutation.
Raad N, Bittihn P, Cacheux M, Jeong D, Ilkan Z, Ceholski D, Kohlbrenner E, Zhang L, Cai CL, Kranias EG, Hajjar RJ, Stillitano F, Akar FG. Raad N, et al. Among authors: kohlbrenner e. Circulation. 2021 Aug 10;144(6):441-454. doi: 10.1161/CIRCULATIONAHA.119.043502. Epub 2021 May 24. Circulation. 2021. PMID: 34024116 Free PMC article.
AAV1.SERCA2a Gene Therapy Reverses Pulmonary Fibrosis by Blocking the STAT3/FOXM1 Pathway and Promoting the SNON/SKI Axis.
Bisserier M, Milara J, Abdeldjebbar Y, Gubara S, Jones C, Bueno-Beti C, Chepurko E, Kohlbrenner E, Katz MG, Tarzami S, Cortijo J, Leopold J, Hajjar RJ, Sassi Y, Hadri L. Bisserier M, et al. Among authors: kohlbrenner e. Mol Ther. 2020 Feb 5;28(2):394-410. doi: 10.1016/j.ymthe.2019.11.027. Epub 2019 Dec 6. Mol Ther. 2020. PMID: 31879190 Free PMC article.
AAV Vectors for Efficient Gene Delivery to Rodent Hearts.
Lopez-Gordo E, Kohlbrenner E, Katz MG, Weber T. Lopez-Gordo E, et al. Among authors: kohlbrenner e. Methods Mol Biol. 2019;1950:311-332. doi: 10.1007/978-1-4939-9139-6_19. Methods Mol Biol. 2019. PMID: 30783983 Free PMC article.
Intra-tracheal gene delivery of aerosolized SERCA2a to the lung suppresses ventricular arrhythmias in a model of pulmonary arterial hypertension.
Strauss B, Sassi Y, Bueno-Beti C, Ilkan Z, Raad N, Cacheux M, Bisserier M, Turnbull IC, Kohlbrenner E, Hajjar RJ, Hadri L, Akar FG. Strauss B, et al. Among authors: kohlbrenner e. J Mol Cell Cardiol. 2019 Feb;127:20-30. doi: 10.1016/j.yjmcc.2018.11.017. Epub 2018 Nov 28. J Mol Cell Cardiol. 2019. PMID: 30502350 Free PMC article.
45 results