Alexander IE - Search Results

1

Liver-specific adiponectin gene therapy suppresses microglial NLRP3-inflammasome activation for treating Alzheimer's disease.

Ng RC, Jian M, Ma OK, Xiang AW, Bunting M, Kwan JS, Wong CW, Yick LW, Chung SK, Lam KS, Alexander IE, Xu A, Chan KH. Ng RC, et al. Among authors: alexander ie. J Neuroinflammation. 2024 Mar 27;21(1):77. doi: 10.1186/s12974-024-03066-y. J Neuroinflammation. 2024. PMID: 38539253 Free PMC article.

2

AAV-Mediated Gene Delivery to the Mouse Liver.

Cunningham SC, Alexander IE. Cunningham SC, et al. Among authors: alexander ie. Methods Mol Biol. 2019;1937:213-219. doi: 10.1007/978-1-4939-9065-8_12. Methods Mol Biol. 2019. PMID: 30706398

3

Development of CNS tropic AAV1-like variants with reduced liver-targeting following systemic administration in mice.

Drouyer M, Merjane J, Nazareth D, Knight M, Scott S, Liao SHY, Ginn SL, Zhu E, Alexander IE, Lisowski L. Drouyer M, et al. Among authors: alexander ie. Mol Ther. 2024 Mar 6;32(3):818-836. doi: 10.1016/j.ymthe.2024.01.024. Epub 2024 Feb 1. Mol Ther. 2024. PMID: 38297833 Free article.

4

AAV-delivered hepato-adrenal cooperativity in steroidogenesis: Implications for gene therapy for congenital adrenal hyperplasia.

Graves LE, van Dijk EB, Zhu E, Koyyalamudi S, Wotton T, Sung D, Srinivasan S, Ginn SL, Alexander IE. Graves LE, et al. Among authors: alexander ie. Mol Ther Methods Clin Dev. 2024 Mar 12;32(2):101232. doi: 10.1016/j.omtm.2024.101232. eCollection 2024 Jun 13. Mol Ther Methods Clin Dev. 2024. PMID: 38558568 Free PMC article.

5

Gene delivery to the juvenile mouse liver using AAV2/8 vectors.

Cunningham SC, Dane AP, Spinoulas A, Logan GJ, Alexander IE. Cunningham SC, et al. Among authors: alexander ie. Mol Ther. 2008 Jun;16(6):1081-8. doi: 10.1038/mt.2008.72. Epub 2008 Apr 15. Mol Ther. 2008. PMID: 18414478 Free article.

6

Gene therapy: progress in childhood disease.

Ginn SL, Alexander IE. Ginn SL, et al. Among authors: alexander ie. J Paediatr Child Health. 2012 Jun;48(6):466-71. doi: 10.1111/j.1440-1754.2011.02204.x. Epub 2011 Oct 21. J Paediatr Child Health. 2012. PMID: 22017270 Review.

7

Comparison of gene transfer to the murine liver following intraperitoneal and intraportal delivery of hepatotropic AAV pseudo-serotypes.

Dane AP, Wowro SJ, Cunningham SC, Alexander IE. Dane AP, et al. Among authors: alexander ie. Gene Ther. 2013 Apr;20(4):460-4. doi: 10.1038/gt.2012.67. Epub 2012 Aug 16. Gene Ther. 2013. PMID: 22895507

8

Prevention of Cholestatic Liver Disease and Reduced Tumorigenicity in a Murine Model of PFIC Type 3 Using Hybrid AAV-piggyBac Gene Therapy.

Siew SM, Cunningham SC, Zhu E, Tay SS, Venuti E, Bolitho C, Alexander IE. Siew SM, et al. Among authors: alexander ie. Hepatology. 2019 Dec;70(6):2047-2061. doi: 10.1002/hep.30773. Epub 2019 Jun 26. Hepatology. 2019. PMID: 31099022

9

Insights into Gene Therapy for Urea Cycle Defects by Mathematical Modeling.

Kok CY, Cunningham SC, Kuchel PW, Alexander IE. Kok CY, et al. Among authors: alexander ie. Hum Gene Ther. 2019 Nov;30(11):1385-1394. doi: 10.1089/hum.2019.053. Epub 2019 Jul 17. Hum Gene Ther. 2019. PMID: 31215258

10

Conversion of the Liver into a Biofactory for DNaseI Using Adeno-Associated Virus Vector Gene Transfer Reduces Neutrophil Extracellular Traps in a Model of Systemic Lupus Erythematosus.

Ahmad A, Mandwie M, O'Sullivan KM, Smyth C, York J, Doyle H, Holdsworth SR, Pickering MC, Lachmann PJ, Alexander IE, Logan GJ. Ahmad A, et al. Among authors: alexander ie. Hum Gene Ther. 2022 May;33(9-10):560-571. doi: 10.1089/hum.2021.264. Hum Gene Ther. 2022. PMID: 35293226

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