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Page 1
Attenuation of fibroblast activation and fibrosis by adropin in systemic sclerosis.
Liang M, Dickel N, Györfi AH, SafakTümerdem B, Li YN, Rigau AR, Liang C, Hong X, Shen L, Matei AE, Trinh-Minh T, Tran-Manh C, Zhou X, Zehender A, Kreuter A, Zou H, Schett G, Kunz M, Distler JHW. Liang M, et al. Among authors: li yn. Sci Transl Med. 2024 Mar 27;16(740):eadd6570. doi: 10.1126/scitranslmed.add6570. Epub 2024 Mar 27. Sci Transl Med. 2024. PMID: 38536934
The tyrosine phosphatase SHP2 controls TGFβ-induced STAT3 signaling to regulate fibroblast activation and fibrosis.
Zehender A, Huang J, Györfi AH, Matei AE, Trinh-Minh T, Xu X, Li YN, Chen CW, Lin J, Dees C, Beyer C, Gelse K, Zhang ZY, Bergmann C, Ramming A, Birchmeier W, Distler O, Schett G, Distler JHW. Zehender A, et al. Among authors: li yn. Nat Commun. 2018 Aug 14;9(1):3259. doi: 10.1038/s41467-018-05768-3. Nat Commun. 2018. PMID: 30108215 Free PMC article.
Vascularised human skin equivalents as a novel in vitro model of skin fibrosis and platform for testing of antifibrotic drugs.
Matei AE, Chen CW, Kiesewetter L, Györfi AH, Li YN, Trinh-Minh T, Xu X, Tran Manh C, van Kuppevelt T, Hansmann J, Jüngel A, Schett G, Groeber-Becker F, Distler JHW. Matei AE, et al. Among authors: li yn. Ann Rheum Dis. 2019 Dec;78(12):1686-1692. doi: 10.1136/annrheumdis-2019-216108. Epub 2019 Sep 20. Ann Rheum Dis. 2019. PMID: 31540936
Fibroblast growth factor receptor 3 activates a network of profibrotic signaling pathways to promote fibrosis in systemic sclerosis.
Chakraborty D, Zhu H, Jüngel A, Summa L, Li YN, Matei AE, Zhou X, Huang J, Trinh-Minh T, Chen CW, Lafyatis R, Dees C, Bergmann C, Soare A, Luo H, Ramming A, Schett G, Distler O, Distler JHW. Chakraborty D, et al. Among authors: li yn. Sci Transl Med. 2020 Sep 30;12(563):eaaz5506. doi: 10.1126/scitranslmed.aaz5506. Sci Transl Med. 2020. PMID: 32998972
TGFβ promotes fibrosis by MYST1-dependent epigenetic regulation of autophagy.
Zehender A, Li YN, Lin NY, Stefanica A, Nüchel J, Chen CW, Hsu HH, Zhu H, Ding X, Huang J, Shen L, Györfi AH, Soare A, Rauber S, Bergmann C, Ramming A, Plomann M, Eckes B, Schett G, Distler JHW. Zehender A, et al. Among authors: li yn. Nat Commun. 2021 Jul 20;12(1):4404. doi: 10.1038/s41467-021-24601-y. Nat Commun. 2021. PMID: 34285225 Free PMC article.
Characterization of Vascular Niche in Systemic Sclerosis by Spatial Proteomics.
Rius Rigau A, Li YN, Matei AE, Györfi AH, Bruch PM, Koziel S, Devakumar V, Gabrielli A, Kreuter A, Wang J, Dietrich S, Schett G, Distler JHW, Liang M. Rius Rigau A, et al. Among authors: li yn. Circ Res. 2024 Mar 29;134(7):875-891. doi: 10.1161/CIRCRESAHA.123.323299. Epub 2024 Mar 5. Circ Res. 2024. PMID: 38440901 Free article.
Combined inhibition of IL-1, IL-33 and IL-36 signalling by targeting IL1RAP ameliorates skin and lung fibrosis in preclinical models of systemic sclerosis.
Grönberg C, Rattik S, Tran-Manh C, Zhou X, Rius Rigau A, Li YN, Györfi AH, Dickel N, Kunz M, Kreuter A, Matei EA, Zhu H, Skoog P, Liberg D, Distler JH, Trinh-Minh T. Grönberg C, et al. Among authors: li yn. Ann Rheum Dis. 2024 Apr 9:ard-2023-225158. doi: 10.1136/ard-2023-225158. Online ahead of print. Ann Rheum Dis. 2024. PMID: 38594058 Free article.
772 results