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An injury-induced tissue niche shaped by mesenchymal plasticity coordinates the regenerative and disease response in the lung.
Jones DL, Morley MP, Li X, Ying Y, Cardenas-Diaz FL, Li S, Zhou S, Schaefer SE, Chembazhi UV, Nottingham A, Lin S, Cantu E, Diamond JM, Basil MC, Vaughan AE, Morrisey EE. Jones DL, et al. Among authors: vaughan ae. bioRxiv [Preprint]. 2024 Feb 29:2024.02.26.582147. doi: 10.1101/2024.02.26.582147. bioRxiv. 2024. PMID: 38529490 Free PMC article. Preprint.
Microstructured Hydrogels to Guide Self-Assembly and Function of Lung Alveolospheres.
Loebel C, Weiner AI, Eiken MK, Katzen JB, Morley MP, Bala V, Cardenas-Diaz FL, Davidson MD, Shiraishi K, Basil MC, Ferguson LT, Spence JR, Ochs M, Beers MF, Morrisey EE, Vaughan AE, Burdick JA. Loebel C, et al. Among authors: vaughan ae. Adv Mater. 2022 Jul;34(28):e2202992. doi: 10.1002/adma.202202992. Epub 2022 Jun 7. Adv Mater. 2022. PMID: 35522531 Free PMC article.
Vascular Endothelial-derived SPARCL1 Exacerbates Viral Pneumonia Through Pro-Inflammatory Macrophage Activation.
Zhao G, Gentile ME, Xue L, Cosgriff CV, Weiner AI, Adams-Tzivelekidis S, Wong J, Li X, Kass-Gergi S, Holcomb NP, Basal MC, Stewart KM, Planer JD, Cantu E, Christie JD, Crespo MM, Mitchell MJ, Meyer NJ, Vaughan AE. Zhao G, et al. Among authors: vaughan ae. bioRxiv [Preprint]. 2023 May 25:2023.05.25.541966. doi: 10.1101/2023.05.25.541966. bioRxiv. 2023. PMID: 37292817 Free PMC article. Updated. Preprint.
TGF-βR2 signaling coordinates pulmonary vascular repair after viral injury in mice and human tissue.
Zhao G, Xue L, Weiner AI, Gong N, Adams-Tzivelekidis S, Wong J, Gentile ME, Nottingham AN, Basil MC, Lin SM, Niethamer TK, Diamond JM, Bermudez CA, Cantu E, Han X, Cao Y, Alameh MG, Weissman D, Morrisey EE, Mitchell MJ, Vaughan AE. Zhao G, et al. Among authors: vaughan ae. Sci Transl Med. 2024 Jan 31;16(732):eadg6229. doi: 10.1126/scitranslmed.adg6229. Epub 2024 Jan 31. Sci Transl Med. 2024. PMID: 38295183
Vascular endothelial-derived SPARCL1 exacerbates viral pneumonia through pro-inflammatory macrophage activation.
Zhao G, Gentile ME, Xue L, Cosgriff CV, Weiner AI, Adams-Tzivelekidis S, Wong J, Li X, Kass-Gergi S, Holcomb NP, Basal MC, Stewart KM, Planer JD, Cantu E, Christie JD, Crespo MM, Mitchell MJ, Meyer NJ, Vaughan AE. Zhao G, et al. Among authors: vaughan ae. Nat Commun. 2024 May 18;15(1):4235. doi: 10.1038/s41467-024-48589-3. Nat Commun. 2024. PMID: 38762489 Free PMC article.
Mesenchyme-free expansion and transplantation of adult alveolar progenitor cells: steps toward cell-based regenerative therapies.
Weiner AI, Jackson SR, Zhao G, Quansah KK, Farshchian JN, Neupauer KM, Littauer EQ, Paris AJ, Liberti DC, Scott Worthen G, Morrisey EE, Vaughan AE. Weiner AI, et al. Among authors: vaughan ae. NPJ Regen Med. 2019 Aug 20;4:17. doi: 10.1038/s41536-019-0080-9. eCollection 2019. NPJ Regen Med. 2019. PMID: 31452939 Free PMC article.
Impaired AMPK Control of Alveolar Epithelial Cell Metabolism Promotes Pulmonary Fibrosis.
Rodriguez LR, Alysandratos KD, Katzen J, Murthy A, Barboza WR, Tomer Y, Acin-Perez R, Petcherski A, Minakin K, Carson P, Iyer S, Chavez K, Cooper CH, Babu A, Weiner AI, Vaughan AE, Arany Z, Shirihai OS, Kotton DN, Beers MF. Rodriguez LR, et al. Among authors: vaughan ae. bioRxiv [Preprint]. 2024 Mar 28:2024.03.26.586649. doi: 10.1101/2024.03.26.586649. bioRxiv. 2024. PMID: 38585863 Free PMC article. Preprint.
Regenerative activity of the lung after epithelial injury.
Vaughan AE, Chapman HA. Vaughan AE, et al. Biochim Biophys Acta. 2013 Jul;1832(7):922-30. doi: 10.1016/j.bbadis.2012.11.020. Epub 2012 Dec 5. Biochim Biophys Acta. 2013. PMID: 23219956 Free article. Review.
42 results