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Page 1
Trametinib sensitizes KRAS-mutant lung adenocarcinoma tumors to PD-1/PD-L1 axis blockade via Id1 downregulation.
Puyalto A, Rodríguez-Remírez M, López I, Macaya I, Guruceaga E, Olmedo M, Vilalta-Lacarra A, Welch C, Sandiego S, Vicent S, Valencia K, Calvo A, Pio R, Raez LE, Rolfo C, Ajona D, Gil-Bazo I. Puyalto A, et al. Among authors: macaya i. Mol Cancer. 2024 Apr 20;23(1):78. doi: 10.1186/s12943-024-01991-3. Mol Cancer. 2024. PMID: 38643157 Free PMC article.
RhoA downregulation in the murine intestinal epithelium results in chronic Wnt activation and increased tumorigenesis.
Dopeso H, Rodrigues P, Cartón-García F, Macaya I, Bilic J, Anguita E, Jing L, Brotons B, Vivancos N, Beà L, Sánchez-Martín M, Landolfi S, Hernandez-Losa J, Ramon Y Cajal S, Nieto R, Vicario M, Farre R, Schwartz S Jr, van Ijzendoorn SCD, Kobayashi K, Martinez-Barriocanal Á, Arango D. Dopeso H, et al. Among authors: macaya i. iScience. 2024 Mar 1;27(4):109400. doi: 10.1016/j.isci.2024.109400. eCollection 2024 Apr 19. iScience. 2024. PMID: 38523777 Free PMC article.
Signature-driven repurposing of Midostaurin for combination with MEK1/2 and KRASG12C inhibitors in lung cancer.
Macaya I, Roman M, Welch C, Entrialgo-Cadierno R, Salmon M, Santos A, Feliu I, Kovalski J, Lopez I, Rodriguez-Remirez M, Palomino-Echeverria S, Lonfgren SM, Ferrero M, Calabuig S, Ludwig IA, Lara-Astiaso D, Jantus-Lewintre E, Guruceaga E, Narayanan S, Ponz-Sarvise M, Pineda-Lucena A, Lecanda F, Ruggero D, Khatri P, Santamaria E, Fernandez-Irigoyen J, Ferrer I, Paz-Ares L, Drosten M, Barbacid M, Gil-Bazo I, Vicent S. Macaya I, et al. Nat Commun. 2023 Oct 10;14(1):6332. doi: 10.1038/s41467-023-41828-z. Nat Commun. 2023. PMID: 37816716 Free PMC article.
Correction: The phospholipid transporter PITPNC1 links KRAS to MYC to prevent autophagy in lung and pancreatic cancer.
Entrialgo-Cadierno R, Cueto-Ureña C, Welch C, Feliu I, Macaya I, Vera L, Morales X, Michelina SV, Scaparone P, Lopez I, Darbo E, Erice O, Vallejo A, Moreno H, Goñi-Salaverri A, Lara-Astiaso D, Halberg N, Cortes-Dominguez I, Guruceaga E, Ambrogio C, Lecanda F, Vicent S. Entrialgo-Cadierno R, et al. Among authors: macaya i. Mol Cancer. 2023 Jun 16;22(1):97. doi: 10.1186/s12943-023-01795-x. Mol Cancer. 2023. PMID: 37328838 Free PMC article. No abstract available.
The phospholipid transporter PITPNC1 links KRAS to MYC to prevent autophagy in lung and pancreatic cancer.
Entrialgo-Cadierno R, Cueto-Ureña C, Welch C, Feliu I, Macaya I, Vera L, Morales X, Michelina SV, Scaparone P, Lopez I, Darbo E, Erice O, Vallejo A, Moreno H, Goñi-Salaverri A, Lara-Astiaso D, Halberg N, Cortes-Dominguez I, Guruceaga E, Ambrogio C, Lecanda F, Vicent S. Entrialgo-Cadierno R, et al. Among authors: macaya i. Mol Cancer. 2023 May 20;22(1):86. doi: 10.1186/s12943-023-01788-w. Mol Cancer. 2023. PMID: 37210549 Free PMC article.
LAMC2 Regulates Key Transcriptional and Targetable Effectors to Support Pancreatic Cancer Growth.
Erice O, Narayanan S, Feliu I, Entrialgo-Cadierno R, Malinova A, Vicentini C, Guruceaga E, Delfino P, Trajkovic-Arsic M, Moreno H, Valencia K, Blanco E, Macaya I, Öhlund D, Khatri P, Lecanda F, Scarpa A, Siveke JT, Corbo V, Ponz-Sarvise M, Vicent S. Erice O, et al. Among authors: macaya i. Clin Cancer Res. 2023 Mar 14;29(6):1137-1154. doi: 10.1158/1078-0432.CCR-22-0794. Clin Cancer Res. 2023. PMID: 36607777
Myosin Vb as a tumor suppressor gene in intestinal cancer.
Cartón-García F, Brotons B, Anguita E, Dopeso H, Tarragona J, Nieto R, García-Vidal E, Macaya I, Zagyva Z, Dalmau M, Sánchez-Martín M, van Ijzendoorn SCD, Landolfi S, Hernandez-Losa J, Schwartz S Jr, Matias-Guiu X, Ramón Y Cajal S, Martínez-Barriocanal Á, Arango D. Cartón-García F, et al. Among authors: macaya i. Oncogene. 2022 Dec;41(49):5279-5288. doi: 10.1038/s41388-022-02508-2. Epub 2022 Nov 1. Oncogene. 2022. PMID: 36316444
FRAGILE-COLCOVID19: A Clinical Trial Based on Early Administration of an Oral Combination of Colchicine and Prednisone in Elderly Patients with COVID-19 in Geriatric Facilities.
Hernández-Rodríguez J, Durán-Sanclemente J, Prieto-González S, Araújo O, Hospital-Vidal T, Casanovas G, Sapena V, Blanco JL, López-Soto A; FRAGILE-COLCOVID19 Study Group. Hernández-Rodríguez J, et al. Clin Drug Investig. 2022 Nov;42(11):949-964. doi: 10.1007/s40261-022-01201-2. Epub 2022 Sep 29. Clin Drug Investig. 2022. PMID: 36173596 Free PMC article. Clinical Trial.
Impact of SARS-CoV-2 viral load and duration of symptoms before hospital admission on the mortality of hospitalized COVID-19 patients.
Rico-Caballero V, Fernández M, Hurtado JC, Marcos MA, Cardozo C, Albiach L, Agüero D, Ambrosioni J, Bodro M, Chumbita M, De la Mora L, Garcia-Pouton N, Gonzalez-Cordón A, Dueñas G, Hernandez-Meneses M, Inciarte A, Laguno M, Leal L, Macaya I, Martínez MJ, Cuesta G, Meira F, Morata L, Puerta-Alcalde P, Rojas J, Torres B, Castro P, Muñoz J, Mensa J, Martínez JA, Sanjuan G, Vila J, García F, Garcia-Vidal C, Soriano A; COVID-19-Researcher Group. Rico-Caballero V, et al. Among authors: macaya i. Infection. 2022 Oct;50(5):1321-1328. doi: 10.1007/s15010-022-01833-8. Epub 2022 May 13. Infection. 2022. PMID: 35562568 Free PMC article.
Clinical Presentation and Outcome of COVID-19 in a Latin American Versus Spanish Population: Matched Case-Control Study.
Alonso R, Camon AM, Cardozo C, Albiach L, Agüero D, Marcos MA, Ambrosioni J, Bodro M, Chumbita M, de la Mora L, Garcia-Pouton N, Dueñas G, Hernandez-Meneses M, Inciarte A, Cuesta G, Meira F, Morata L, Puerta-Alcalde P, Herrera S, Tuset M, Castro P, Prieto-Gonzalez S, Mensa J, Martínez JA, Sanjuan G, Nicolas JM, Del Rio A, Vila J, Garcia F, Garcia-Vidal C, Soriano A; Hospital Clinic of Barcelona COVID-19 research group. Alonso R, et al. Infect Dis Ther. 2022 Jun;11(3):1243-1251. doi: 10.1007/s40121-022-00623-x. Epub 2022 Apr 27. Infect Dis Ther. 2022. PMID: 35476212 Free PMC article.
30 results