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Prehospital tranexamic acid is associated with a survival benefit without an increase in complications: results of two harmonized randomized clinical trials.
Mazzei M, Donohue JK, Schreiber M, Rowell S, Guyette FX, Cotton B, Eastridge BJ, Nirula R, Vercruysse GA, O'Keeffe T, Joseph B, Brown JB, Neal MD, Sperry JL. Mazzei M, et al. Among authors: o keeffe t. J Trauma Acute Care Surg. 2024 Mar 25. doi: 10.1097/TA.0000000000004315. Online ahead of print. J Trauma Acute Care Surg. 2024. PMID: 38523128
Tranexamic Acid During Prehospital Transport in Patients at Risk for Hemorrhage After Injury: A Double-blind, Placebo-Controlled, Randomized Clinical Trial.
Guyette FX, Brown JB, Zenati MS, Early-Young BJ, Adams PW, Eastridge BJ, Nirula R, Vercruysse GA, O'Keeffe T, Joseph B, Alarcon LH, Callaway CW, Zuckerbraun BS, Neal MD, Forsythe RM, Rosengart MR, Billiar TR, Yealy DM, Peitzman AB, Sperry JL; STAAMP Study Group. Guyette FX, et al. JAMA Surg. 2020 Oct 5;156(1):11-20. doi: 10.1001/jamasurg.2020.4350. Online ahead of print. JAMA Surg. 2020. PMID: 33016996 Free PMC article.
Prehospital tranexamic acid is associated with a dose-dependent decrease in syndecan-1 after trauma: A secondary analysis of a prospective randomized trial.
Gruen DS, Brown JB, Guyette FX, Johansson PI, Stensballe J, Li SR, Leeper CM, Eastridge BJ, Nirula R, Vercruysse GA, O'Keeffe T, Joseph B, Neal MD, Sperry JL. Gruen DS, et al. Among authors: o keeffe t. J Trauma Acute Care Surg. 2023 Nov 1;95(5):642-648. doi: 10.1097/TA.0000000000003955. Epub 2023 May 1. J Trauma Acute Care Surg. 2023. PMID: 37125811 Free PMC article. Clinical Trial.
Missingness matters: a secondary analysis of thromboelastography measurements from a recent prehospital randomized tranexamic acid clinical trial.
Donohue JK, Iyanna N, Lorence JM, Brown JB, Guyette FX, Eastridge BJ, Nirula R, Vercruysse GA, O'Keeffe T, Joseph B, Neal MD, Sperry JL. Donohue JK, et al. Among authors: o keeffe t. Trauma Surg Acute Care Open. 2024 Feb 17;9(1):e001346. doi: 10.1136/tsaco-2023-001346. eCollection 2024. Trauma Surg Acute Care Open. 2024. PMID: 38375027 Free PMC article.
230 results