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Prior infection with unrelated neurotropic virus exacerbates influenza disease and impairs lung T cell responses.
Foo IJ, Chua BY, Clemens EB, Chang SY, Jia X, McQuilten HA, Yap AHY, Cabug AF, Ashayeripanah M, McWilliam HEG, Villadangos JA, Evrard M, Mackay LK, Wakim LM, Fazakerley JK, Kedzierska K, Kedzierski L. Foo IJ, et al. Among authors: jia x. Nat Commun. 2024 Mar 23;15(1):2619. doi: 10.1038/s41467-024-46822-7. Nat Commun. 2024. PMID: 38521764 Free PMC article.
Immune cellular networks underlying recovery from influenza virus infection in acute hospitalized patients.
Nguyen THO, Koutsakos M, van de Sandt CE, Crawford JC, Loh L, Sant S, Grzelak L, Allen EK, Brahm T, Clemens EB, Auladell M, Hensen L, Wang Z, Nüssing S, Jia X, Günther P, Wheatley AK, Kent SJ, Aban M, Deng YM, Laurie KL, Hurt AC, Gras S, Rossjohn J, Crowe J, Xu J, Jackson D, Brown LE, La Gruta N, Chen W, Doherty PC, Turner SJ, Kotsimbos TC, Thomas PG, Cheng AC, Kedzierska K. Nguyen THO, et al. Among authors: jia x. Nat Commun. 2021 May 11;12(1):2691. doi: 10.1038/s41467-021-23018-x. Nat Commun. 2021. PMID: 33976217 Free PMC article.
Newborn and child-like molecular signatures in older adults stem from TCR shifts across human lifespan.
van de Sandt CE, Nguyen THO, Gherardin NA, Crawford JC, Samir J, Minervina AA, Pogorelyy MV, Rizzetto S, Szeto C, Kaur J, Ranson N, Sonda S, Harper A, Redmond SJ, McQuilten HA, Menon T, Sant S, Jia X, Pedrina K, Karapanagiotidis T, Cain N, Nicholson S, Chen Z, Lim R, Clemens EB, Eltahla A, La Gruta NL, Crowe J, Lappas M, Rossjohn J, Godfrey DI, Thomas PG, Gras S, Flanagan KL, Luciani F, Kedzierska K. van de Sandt CE, et al. Among authors: jia x. Nat Immunol. 2023 Nov;24(11):1890-1907. doi: 10.1038/s41590-023-01633-8. Epub 2023 Sep 25. Nat Immunol. 2023. PMID: 37749325 Free PMC article.
MAIT cells contribute to protection against lethal influenza infection in vivo.
van Wilgenburg B, Loh L, Chen Z, Pediongco TJ, Wang H, Shi M, Zhao Z, Koutsakos M, Nüssing S, Sant S, Wang Z, D'Souza C, Jia X, Almeida CF, Kostenko L, Eckle SBG, Meehan BS, Kallies A, Godfrey DI, Reading PC, Corbett AJ, McCluskey J, Klenerman P, Kedzierska K, Hinks TSC. van Wilgenburg B, et al. Among authors: jia x. Nat Commun. 2018 Nov 9;9(1):4706. doi: 10.1038/s41467-018-07207-9. Nat Commun. 2018. PMID: 30413689 Free PMC article.
TLR2-mediated activation of innate responses in the upper airways confers antiviral protection of the lungs.
Deliyannis G, Wong CY, McQuilten HA, Bachem A, Clarke M, Jia X, Horrocks K, Zeng W, Girkin J, Scott NE, Londrigan SL, Reading PC, Bartlett NW, Kedzierska K, Brown LE, Mercuri F, Demaison C, Jackson DC, Chua BY. Deliyannis G, et al. Among authors: jia x. JCI Insight. 2021 Mar 8;6(5):e140267. doi: 10.1172/jci.insight.140267. JCI Insight. 2021. PMID: 33561017 Free PMC article.
SARS-CoV-2-specific T cell memory with common TCRαβ motifs is established in unvaccinated children who seroconvert after infection.
Rowntree LC, Nguyen THO, Kedzierski L, Neeland MR, Petersen J, Crawford JC, Allen LF, Clemens EB, Chua B, McQuilten HA, Minervina AA, Pogorelyy MV, Chaurasia P, Tan HX, Wheatley AK, Jia X, Amanat F, Krammer F, Allen EK, Sonda S, Flanagan KL, Jumarang J, Pannaraj PS, Licciardi PV, Kent SJ, Bond KA, Williamson DA, Rossjohn J, Thomas PG, Tosif S, Crawford NW, van de Sandt CE, Kedzierska K. Rowntree LC, et al. Among authors: jia x. Immunity. 2022 Jul 12;55(7):1299-1315.e4. doi: 10.1016/j.immuni.2022.06.003. Epub 2022 Jun 8. Immunity. 2022. PMID: 35750048 Free PMC article.
Robust SARS-CoV-2 T cell responses with common TCRαβ motifs toward COVID-19 vaccines in patients with hematological malignancy impacting B cells.
Nguyen THO, Rowntree LC, Allen LF, Chua BY, Kedzierski L, Lim C, Lasica M, Tennakoon GS, Saunders NR, Crane M, Chee L, Seymour JF, Anderson MA, Whitechurch A, Clemens EB, Zhang W, Chang SY, Habel JR, Jia X, McQuilten HA, Minervina AA, Pogorelyy MV, Chaurasia P, Petersen J, Menon T, Hensen L, Neil JA, Mordant FL, Tan HX, Cabug AF, Wheatley AK, Kent SJ, Subbarao K, Karapanagiotidis T, Huang H, Vo LK, Cain NL, Nicholson S, Krammer F, Gibney G, James F, Trevillyan JM, Trubiano JA, Mitchell J, Christensen B, Bond KA, Williamson DA, Rossjohn J, Crawford JC, Thomas PG, Thursky KA, Slavin MA, Tam CS, Teh BW, Kedzierska K. Nguyen THO, et al. Among authors: jia x. Cell Rep Med. 2023 Apr 18;4(4):101017. doi: 10.1016/j.xcrm.2023.101017. Epub 2023 Mar 27. Cell Rep Med. 2023. PMID: 37030296 Free PMC article.
Immune profiling of SARS-CoV-2 infection during pregnancy reveals NK cell and γδ T cell perturbations.
Habel JR, Chua BY, Kedzierski L, Selva KJ, Damelang T, Haycroft ER, Nguyen TH, Koay HF, Nicholson S, McQuilten HA, Jia X, Allen LF, Hensen L, Zhang W, van de Sandt CE, Neil JA, Pragastis K, Lau JS, Jumarang J, Allen EK, Amanant F, Krammer F, Wragg KM, Juno JA, Wheatley AK, Tan HX, Pell G, Walker S, Audsley J, Reynaldi A, Thevarajan I, Denholm JT, Subbarao K, Davenport MP, Hogarth PM, Godfrey DI, Cheng AC, Tong SY, Bond K, Williamson DA, McMahon JH, Thomas PG, Pannaraj PS, James F, Holmes NE, Smibert OC, Trubiano JA, Gordon CL, Chung AW, Whitehead CL, Kent SJ, Lappas M, Rowntree LC, Kedzierska K. Habel JR, et al. Among authors: jia x. JCI Insight. 2023 Apr 10;8(7):e167157. doi: 10.1172/jci.insight.167157. JCI Insight. 2023. PMID: 37036008 Free PMC article.
9,131 results