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Page 1
A Pfs48/45-based vaccine to block Plasmodium falciparum transmission: phase 1, open-label, clinical trial.
Alkema M, Smit MJ, Marin-Mogollon C, Totté K, Teelen K, van Gemert GJ, van de Vegte-Bolmer M, Mordmüller BG, Reimer JM, Lövgren-Bengtsson KL, Sauerwein RW, Bousema T, Plieskatt J, Theisen M, Jore MM, McCall MBB. Alkema M, et al. Among authors: van de vegte bolmer m. BMC Med. 2024 Apr 23;22(1):170. doi: 10.1186/s12916-024-03379-y. BMC Med. 2024. PMID: 38649867 Free PMC article. Clinical Trial.
Quantification of sporozoite expelling by Anopheles mosquitoes infected with laboratory and naturally circulating P. falciparum gametocytes.
Andolina C, Graumans W, Guelbeogo M, van Gemert GJ, Ramijth J, Harouna S, Soumanaba Z, Stoter R, Vegte-Bolmer M, Pangos M, Sinnis P, Collins K, Staedke SG, Tiono AB, Drakeley C, Lanke K, Bousema T. Andolina C, et al. Among authors: vegte bolmer m. Elife. 2024 Mar 22;12:RP90989. doi: 10.7554/eLife.90989. Elife. 2024. PMID: 38517746 Free PMC article.
Detailing organelle division and segregation in Plasmodium falciparum.
Verhoef JMJ, Boshoven C, Evers F, Akkerman LJ, Gijsbrechts BCA, van de Vegte-Bolmer M, van Gemert GJ, Vaidya AB, Kooij TWA. Verhoef JMJ, et al. Among authors: van de vegte bolmer m. bioRxiv [Preprint]. 2024 May 13:2024.01.30.577899. doi: 10.1101/2024.01.30.577899. bioRxiv. 2024. PMID: 38352445 Free PMC article. Preprint.
Pfs230 Domain 7 is targeted by a potent malaria transmission-blocking monoclonal antibody.
Inklaar MR, de Jong RM, Bekkering ET, Nagaoka H, Fennemann FL, Teelen K, van de Vegte-Bolmer M, van Gemert GJ, Stoter R, King CR, Proellochs NI, Bousema T, Takashima E, Tsuboi T, Jore MM. Inklaar MR, et al. Among authors: van de vegte bolmer m. NPJ Vaccines. 2023 Dec 12;8(1):186. doi: 10.1038/s41541-023-00784-x. NPJ Vaccines. 2023. PMID: 38086855 Free PMC article.
Rapid profiling of Plasmodium parasites from genome sequences to assist malaria control.
Phelan JE, Turkiewicz A, Manko E, Thorpe J, Vanheer LN, van de Vegte-Bolmer M, Ngoc NTH, Binh NTH, Thieu NQ, Gitaka J, Nolder D, Beshir KB, Dombrowski JG, Di Santi SM, Bousema T, Sutherland CJ, Campino S, Clark TG. Phelan JE, et al. Among authors: van de vegte bolmer m. Genome Med. 2023 Nov 10;15(1):96. doi: 10.1186/s13073-023-01247-7. Genome Med. 2023. PMID: 37950308 Free PMC article.
Whole sporozoite immunization with Plasmodium falciparum strain NF135 in a randomized trial.
van der Boor SC, Alkema M, van Gemert GJ, Teelen K, van de Vegte-Bolmer M, Walk J, van Crevel R, de Mast Q, Ockenhouse CF, Sauerwein RW, McCall MBB. van der Boor SC, et al. Among authors: van de vegte bolmer m. BMC Med. 2023 Apr 7;21(1):137. doi: 10.1186/s12916-023-02788-9. BMC Med. 2023. PMID: 37024868 Free PMC article. Clinical Trial.
Potent transmission-blocking monoclonal antibodies from naturally exposed individuals target a conserved epitope on Plasmodium falciparum Pfs230.
Ivanochko D, Fabra-García A, Teelen K, van de Vegte-Bolmer M, van Gemert GJ, Newton J, Semesi A, de Bruijni M, Bolscher J, Ramjith J, Szabat M, Vogt S, Kraft L, Duncan S, Lee SM, Kamya MR, Feeney ME, Jagannathan P, Greenhouse B, Sauerwein RW, Richter King C, MacGill RS, Bousema T, Jore MM, Julien JP. Ivanochko D, et al. Among authors: van de vegte bolmer m. Immunity. 2023 Feb 14;56(2):420-432.e7. doi: 10.1016/j.immuni.2023.01.013. Immunity. 2023. PMID: 36792575 Free PMC article.
Highly potent, naturally acquired human monoclonal antibodies against Pfs48/45 block Plasmodium falciparum transmission to mosquitoes.
Fabra-García A, Hailemariam S, de Jong RM, Janssen K, Teelen K, van de Vegte-Bolmer M, van Gemert GJ, Ivanochko D, Semesi A, McLeod B, Vos MW, de Bruijni MHC, Bolscher JM, Szabat M, Vogt S, Kraft L, Duncan S, Kamya MR, Feeney ME, Jagannathan P, Greenhouse B, Dechering KJ, Sauerwein RW, King CR, MacGill RS, Bousema T, Julien JP, Jore MM. Fabra-García A, et al. Among authors: van de vegte bolmer m. Immunity. 2023 Feb 14;56(2):406-419.e7. doi: 10.1016/j.immuni.2023.01.009. Immunity. 2023. PMID: 36792574 Free PMC article.
Vaccination with a structure-based stabilized version of malarial antigen Pfs48/45 elicits ultra-potent transmission-blocking antibody responses.
McLeod B, Mabrouk MT, Miura K, Ravichandran R, Kephart S, Hailemariam S, Pham TP, Semesi A, Kucharska I, Kundu P, Huang WC, Johnson M, Blackstone A, Pettie D, Murphy M, Kraft JC, Leaf EM, Jiao Y, van de Vegte-Bolmer M, van Gemert GJ, Ramjith J, King CR, MacGill RS, Wu Y, Lee KK, Jore MM, King NP, Lovell JF, Julien JP. McLeod B, et al. Among authors: van de vegte bolmer m. Immunity. 2022 Sep 13;55(9):1680-1692.e8. doi: 10.1016/j.immuni.2022.07.015. Epub 2022 Aug 16. Immunity. 2022. PMID: 35977542 Free PMC article.
Safety, tolerability, and Plasmodium falciparum transmission-reducing activity of monoclonal antibody TB31F: a single-centre, open-label, first-in-human, dose-escalation, phase 1 trial in healthy malaria-naive adults.
van der Boor SC, Smit MJ, van Beek SW, Ramjith J, Teelen K, van de Vegte-Bolmer M, van Gemert GJ, Pickkers P, Wu Y, Locke E, Lee SM, Aponte J, King CR, Birkett AJ, Miura K, Ayorinde MA, Sauerwein RW, Ter Heine R, Ockenhouse CF, Bousema T, Jore MM, McCall MBB. van der Boor SC, et al. Among authors: van de vegte bolmer m. Lancet Infect Dis. 2022 Nov;22(11):1596-1605. doi: 10.1016/S1473-3099(22)00428-5. Epub 2022 Aug 10. Lancet Infect Dis. 2022. PMID: 35963275 Free PMC article. Clinical Trial.
80 results