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Review article: New developments in biomarkers and clinical drug development in alpha-1 antitrypsin deficiency-related liver disease.
Loomba R, Clark G, Teckman J, Ajmera V, Behling C, Brantly M, Brenner D, D'Armiento J, Fried MW, Iyer JS, Mandorfer M, Rockey DC, Tincopa M, Vuppalanchi R, Younossi Z, Krag A, Turner AM, Strnad P. Loomba R, et al. Among authors: brantly m. Aliment Pharmacol Ther. 2024 May;59(10):1183-1195. doi: 10.1111/apt.17967. Epub 2024 Mar 22. Aliment Pharmacol Ther. 2024. PMID: 38516814 Review.
Sirtuin3 promotes the degradation of hepatic Z alpha-1 antitrypsin through lipophagy.
Poole B, Oshins R, Huo Z, Aranyos A, West J, Duarte S, Clark VC, Beduschi T, Zarrinpar A, Brantly M, Khodayari N. Poole B, et al. Among authors: brantly m. Hepatol Commun. 2024 Jan 29;8(2):e0370. doi: 10.1097/HC9.0000000000000370. eCollection 2024 Feb 1. Hepatol Commun. 2024. PMID: 38285890 Free PMC article.
Recombinant Alpha-1 Antitrypsin-Fc Fusion Protein INBRX-101 in Adults With Alpha-1 Antitrypsin Deficiency: A Phase 1 Study.
Brantly ML, Kuhn BT, Farah HW, Mahadeva R, Cole A, Chang CL, Brown CD, Campos MA, Lascano JE, Babcock EK, Bhagwat SP, Boyea TF, Veldstra CA, Andrianov V, Kalabus JL, Eckelman BP, Veale AG. Brantly ML, et al. Chronic Obstr Pulm Dis. 2024 May 29;11(3):282-292. doi: 10.15326/jcopdf.2023.0469. Chronic Obstr Pulm Dis. 2024. PMID: 38809792 Free article.
Monocyte NLRP3 inflammasome and interleukin-1β activation modulated by alpha-1 antitrypsin therapy in deficient individuals.
Gogoi D, Yu H, Casey M, Baird R, Yusuf A, Forde L, O' Brien ME, West JR, Flagg T, McElvaney NG, Eden E, Mueller C, Brantly ML, Geraghty P, Reeves EP. Gogoi D, et al. Among authors: brantly ml. Thorax. 2024 Feb 28:thorax-2023-221071. doi: 10.1136/thorax-2023-221071. Online ahead of print. Thorax. 2024. PMID: 38418195 Free article.
Correction to: Cigarette smoke exposed airway epithelial cells-derived EVs promote pro-inflammatory macrophage activation in alpha-1 antitrypsin deficiency.
Khodayari N, Oshins R, Mehrad B, Lascano JE, Qiang X, West JR, Holliday LS, Lee J, Wiesemann G, Eydgahi S, Brantly M. Khodayari N, et al. Among authors: brantly m. Respir Res. 2023 Nov 4;24(1):266. doi: 10.1186/s12931-023-02571-7. Respir Res. 2023. PMID: 37925417 Free PMC article. No abstract available.
190 results