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Paper-based electrochemical device for early detection of integrin αvβ6 expressing tumors.
Cinti S, Tomassi S, Ciardiello C, Migliorino R, Pirozzi M, Leone A, Di Gennaro E, Campani V, De Rosa G, D'Amore VM, Di Maro S, Donati G, Singh S, Raucci A, Di Leva FS, Kessler H, Budillon A, Marinelli L. Cinti S, et al. Among authors: kessler h. Commun Chem. 2024 Mar 21;7(1):60. doi: 10.1038/s42004-024-01144-z. Commun Chem. 2024. PMID: 38514757 Free PMC article.
From a Helix to a Small Cycle: Metadynamics-Inspired αvβ6 Integrin Selective Ligands.
Di Leva FS, Tomassi S, Di Maro S, Reichart F, Notni J, Dangi A, Marelli UK, Brancaccio D, Merlino F, Wester HJ, Novellino E, Kessler H, Marinelli L. Di Leva FS, et al. Among authors: kessler h. Angew Chem Int Ed Engl. 2018 Oct 26;57(44):14645-14649. doi: 10.1002/anie.201803250. Epub 2018 May 2. Angew Chem Int Ed Engl. 2018. PMID: 29660806
Simultaneous Targeting of RGD-Integrins and Dual Murine Double Minute Proteins in Glioblastoma Multiforme.
Merlino F, Daniele S, La Pietra V, Di Maro S, Di Leva FS, Brancaccio D, Tomassi S, Giuntini S, Cerofolini L, Fragai M, Luchinat C, Reichart F, Cavallini C, Costa B, Piccarducci R, Taliani S, Da Settimo F, Martini C, Kessler H, Novellino E, Marinelli L. Merlino F, et al. Among authors: kessler h. J Med Chem. 2018 Jun 14;61(11):4791-4809. doi: 10.1021/acs.jmedchem.8b00004. Epub 2018 Jun 4. J Med Chem. 2018. PMID: 29775303
Halting the Spread of Herpes Simplex Virus-1: The Discovery of an Effective Dual αvβ6/αvβ8 Integrin Ligand.
Tomassi S, D'Amore VM, Di Leva FS, Vannini A, Quilici G, Weinmüller M, Reichart F, Amato J, Romano B, Izzo AA, Di Maro S, Novellino E, Musco G, Gianni T, Kessler H, Marinelli L. Tomassi S, et al. Among authors: kessler h. J Med Chem. 2021 May 27;64(10):6972-6984. doi: 10.1021/acs.jmedchem.1c00533. Epub 2021 May 7. J Med Chem. 2021. PMID: 33961417 Free PMC article.
Selective Targeting of Integrin αvβ8 by a Highly Active Cyclic Peptide.
Reichart F, Maltsev OV, Kapp TG, Räder AFB, Weinmüller M, Marelli UK, Notni J, Wurzer A, Beck R, Wester HJ, Steiger K, Di Maro S, Di Leva FS, Marinelli L, Nieberler M, Reuning U, Schwaiger M, Kessler H. Reichart F, et al. Among authors: kessler h. J Med Chem. 2019 Feb 28;62(4):2024-2037. doi: 10.1021/acs.jmedchem.8b01588. Epub 2019 Feb 6. J Med Chem. 2019. PMID: 30657681
The organometallic ferrocene exhibits amplified anti-tumor activity by targeted delivery via highly selective ligands to αvβ3, αvβ6, or α5β1 integrins.
Ludwig BS, Tomassi S, Di Maro S, Di Leva FS, Benge A, Reichart F, Nieberler M, Kühn FE, Kessler H, Marinelli L, Reuning U, Kossatz S. Ludwig BS, et al. Among authors: kessler h. Biomaterials. 2021 Apr;271:120754. doi: 10.1016/j.biomaterials.2021.120754. Epub 2021 Mar 12. Biomaterials. 2021. PMID: 33756215
1,210 results