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Proinsulin folding and trafficking defects trigger a common pathological disturbance of endoplasmic reticulum homeostasis.
Arunagiri A, Alam M, Haataja L, Draz H, Alasad B, Samy P, Sadique N, Tong Y, Cai Y, Shakeri H, Fantuzzi F, Ibrahim H, Jang I, Sidarala V, Soleimanpour SA, Satin LS, Otonkoski T, Cnop M, Itkin-Ansari P, Kaufman RJ, Liu M, Arvan P. Arunagiri A, et al. Among authors: alam m. Protein Sci. 2024 Apr;33(4):e4949. doi: 10.1002/pro.4949. Protein Sci. 2024. PMID: 38511500 Free PMC article.
Proteasomal degradation of WT proinsulin in pancreatic beta cells.
Xu X, Arunagiri A, Haataja L, Alam M, Ji S, Qi L, Tsai B, Liu M, Arvan P. Xu X, et al. Among authors: alam m. J Biol Chem. 2022 Oct;298(10):102406. doi: 10.1016/j.jbc.2022.102406. Epub 2022 Aug 19. J Biol Chem. 2022. PMID: 35988641 Free PMC article.
Nutrient-dependent regulation of β-cell proinsulin content.
Xu X, Arunagiri A, Alam M, Haataja L, Evans CR, Zhao I, Castro-Gutierrez R, Russ HA, Demangel C, Qi L, Tsai B, Liu M, Arvan P. Xu X, et al. Among authors: alam m. J Biol Chem. 2023 Jul;299(7):104836. doi: 10.1016/j.jbc.2023.104836. Epub 2023 May 19. J Biol Chem. 2023. PMID: 37209827 Free PMC article.
7,601 results