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Towards the competent conformation for catalysis in the ferredoxin-NADP+ reductase from the Brucella ovis pathogen.
Pérez-Amigot D, Taleb V, Boneta S, Anoz-Carbonell E, Sebastián M, Velázquez-Campoy A, Polo V, Martínez-Júlvez M, Medina M. Pérez-Amigot D, et al. Among authors: medina m. Biochim Biophys Acta Bioenerg. 2019 Oct 1;1860(10):148058. doi: 10.1016/j.bbabio.2019.148058. Epub 2019 Aug 5. Biochim Biophys Acta Bioenerg. 2019. PMID: 31394095 Free article.
Structural basis of the pleiotropic and specific phenotypic consequences of missense mutations in the multifunctional NAD(P)H:quinone oxidoreductase 1 and their pharmacological rescue.
Pacheco-Garcia JL, Anoz-Carbonell E, Vankova P, Kannan A, Palomino-Morales R, Mesa-Torres N, Salido E, Man P, Medina M, Naganathan AN, Pey AL. Pacheco-Garcia JL, et al. Among authors: medina m. Redox Biol. 2021 Oct;46:102112. doi: 10.1016/j.redox.2021.102112. Epub 2021 Aug 18. Redox Biol. 2021. PMID: 34537677 Free PMC article.
Different phenotypic outcome due to site-specific phosphorylation in the cancer-associated NQO1 enzyme studied by phosphomimetic mutations.
Pacheco-Garcia JL, Anoz-Carbonell E, Loginov DS, Vankova P, Salido E, Man P, Medina M, Palomino-Morales R, Pey AL. Pacheco-Garcia JL, et al. Among authors: medina m. Arch Biochem Biophys. 2022 Oct 30;729:109392. doi: 10.1016/j.abb.2022.109392. Epub 2022 Sep 9. Arch Biochem Biophys. 2022. PMID: 36096178 Free article.
Beyond a platform protein for the degradosome assembly: The Apoptosis-Inducing Factor as an efficient nuclease involved in chromatinolysis.
Novo N, Romero-Tamayo S, Marcuello C, Boneta S, Blasco-Machin I, Velázquez-Campoy A, Villanueva R, Moreno-Loshuertos R, Lostao A, Medina M, Ferreira P. Novo N, et al. Among authors: medina m. PNAS Nexus. 2022 Dec 26;2(2):pgac312. doi: 10.1093/pnasnexus/pgac312. eCollection 2023 Feb. PNAS Nexus. 2022. PMID: 36845352 Free PMC article.
Structural insights into the synthesis of FMN in prokaryotic organisms.
Herguedas B, Lans I, Sebastián M, Hermoso JA, Martínez-Júlvez M, Medina M. Herguedas B, et al. Among authors: medina m. Acta Crystallogr D Biol Crystallogr. 2015 Dec 1;71(Pt 12):2526-42. doi: 10.1107/S1399004715019641. Epub 2015 Nov 27. Acta Crystallogr D Biol Crystallogr. 2015. PMID: 26627660
2,025 results