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Michael acceptor containing drugs are a novel class of 5-lipoxygenase inhibitor targeting the surface cysteines C416 and C418.
Maucher IV, Rühl M, Kretschmer SB, Hofmann B, Kühn B, Fettel J, Vogel A, Flügel KT, Manolikakes G, Hellmuth N, Häfner AK, Golghalyani V, Ball AK, Piesche M, Matrone C, Geisslinger G, Parnham MJ, Karas M, Steinhilber D, Roos J, Maier TJ. Maucher IV, et al. Among authors: flugel kt. Biochem Pharmacol. 2017 Feb 1;125:55-74. doi: 10.1016/j.bcp.2016.11.004. Epub 2016 Nov 4. Biochem Pharmacol. 2017. PMID: 27823964
The use of an hydrogen peroxide multipurpose isolator for inhouse preparation of human embryo culture media: a unique successful Swiss randomized prospective study.
Van den Bergh MJ, Siragusa A, Dubied A, Vonbach P, Deshe MF, Flügel K, Ruflin S, Stutz J, Teufelberger K, Kratzer A, Urech C, Hohl M. Van den Bergh MJ, et al. Among authors: flugel k. J Assist Reprod Genet. 2004 Nov;21(11):381-6. doi: 10.1007/s10815-004-7525-8. J Assist Reprod Genet. 2004. PMID: 15672950 Free PMC article. Clinical Trial.
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