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CKLF instigates a "cold" microenvironment to promote MYCN-mediated tumor aggressiveness.
Qin X, Lam A, Zhang X, Sengupta S, Iorgulescu JB, Ni H, Das S, Rager M, Zhou Z, Zuo T, Meara GK, Floru AE, Kemet C, Veerapaneni D, Kashy D, Lin L, Lloyd K, Kwok L, Smith KS, Nagaraju RT, Meijers R, Ceol C, Liu CT, Alexandrescu S, Wu CJ, Keskin DB, George RE, Feng H. Qin X, et al. Among authors: wu cj. Sci Adv. 2024 Mar 15;10(11):eadh9547. doi: 10.1126/sciadv.adh9547. Epub 2024 Mar 15. Sci Adv. 2024. PMID: 38489372 Free PMC article.
Mutated BCR-ABL generates immunogenic T-cell epitopes in CML patients.
Cai A, Keskin DB, DeLuca DS, Alonso A, Zhang W, Zhang GL, Hammond NN, Nardi V, Stone RM, Neuberg D, Sidney J, Brusic V, Wu CJ. Cai A, et al. Among authors: wu cj. Clin Cancer Res. 2012 Oct 15;18(20):5761-72. doi: 10.1158/1078-0432.CCR-12-1182. Epub 2012 Aug 21. Clin Cancer Res. 2012. PMID: 22912393 Free PMC article.
Systematic identification of personal tumor-specific neoantigens in chronic lymphocytic leukemia.
Rajasagi M, Shukla SA, Fritsch EF, Keskin DB, DeLuca D, Carmona E, Zhang W, Sougnez C, Cibulskis K, Sidney J, Stevenson K, Ritz J, Neuberg D, Brusic V, Gabriel S, Lander ES, Getz G, Hacohen N, Wu CJ. Rajasagi M, et al. Among authors: wu cj. Blood. 2014 Jul 17;124(3):453-62. doi: 10.1182/blood-2014-04-567933. Epub 2014 Jun 2. Blood. 2014. PMID: 24891321 Free PMC article.
Immunotherapy for glioblastoma: going viral.
Iorgulescu JB, Reardon DA, Chiocca EA, Wu CJ. Iorgulescu JB, et al. Among authors: wu cj. Nat Med. 2018 Aug;24(8):1094-1096. doi: 10.1038/s41591-018-0142-3. Nat Med. 2018. PMID: 30082860 Free PMC article.
A cloning and expression system to probe T-cell receptor specificity and assess functional avidity to neoantigens.
Hu Z, Anandappa AJ, Sun J, Kim J, Leet DE, Bozym DJ, Chen C, Williams L, Shukla SA, Zhang W, Tabbaa D, Steelman S, Olive O, Livak KJ, Kishi H, Muraguchi A, Guleria I, Stevens J, Lane WJ, Burkhardt UE, Fritsch EF, Neuberg D, Ott PA, Keskin DB, Hacohen N, Wu CJ. Hu Z, et al. Among authors: wu cj. Blood. 2018 Nov 1;132(18):1911-1921. doi: 10.1182/blood-2018-04-843763. Epub 2018 Aug 27. Blood. 2018. PMID: 30150207 Free PMC article.
Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial.
Keskin DB, Anandappa AJ, Sun J, Tirosh I, Mathewson ND, Li S, Oliveira G, Giobbie-Hurder A, Felt K, Gjini E, Shukla SA, Hu Z, Li L, Le PM, Allesøe RL, Richman AR, Kowalczyk MS, Abdelrahman S, Geduldig JE, Charbonneau S, Pelton K, Iorgulescu JB, Elagina L, Zhang W, Olive O, McCluskey C, Olsen LR, Stevens J, Lane WJ, Salazar AM, Daley H, Wen PY, Chiocca EA, Harden M, Lennon NJ, Gabriel S, Getz G, Lander ES, Regev A, Ritz J, Neuberg D, Rodig SJ, Ligon KL, Suvà ML, Wucherpfennig KW, Hacohen N, Fritsch EF, Livak KJ, Ott PA, Wu CJ, Reardon DA. Keskin DB, et al. Among authors: wu cj. Nature. 2019 Jan;565(7738):234-239. doi: 10.1038/s41586-018-0792-9. Epub 2018 Dec 19. Nature. 2019. PMID: 30568305 Free PMC article. Clinical Trial.
RNase H-dependent PCR-enabled T-cell receptor sequencing for highly specific and efficient targeted sequencing of T-cell receptor mRNA for single-cell and repertoire analysis.
Li S, Sun J, Allesøe R, Datta K, Bao Y, Oliveira G, Forman J, Jin R, Olsen LR, Keskin DB, Shukla SA, Wu CJ, Livak KJ. Li S, et al. Among authors: wu cj. Nat Protoc. 2019 Aug;14(8):2571-2594. doi: 10.1038/s41596-019-0195-x. Epub 2019 Jul 24. Nat Protoc. 2019. PMID: 31341290 Free PMC article.
1,833 results