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Circulating total and H-specific GDF15 levels are elevated in subjects with MASLD but not in hyperlipidemic but otherwise metabolically healthy subjects with obesity.
Boutari C, Stefanakis K, Simati S, Guatibonza-García V, Valenzuela-Vallejo L, Anastasiou IA, Connelly MA, Kokkinos A, Mantzoros CS. Boutari C, et al. Among authors: stefanakis k. Cardiovasc Diabetol. 2024 May 18;23(1):174. doi: 10.1186/s12933-024-02264-5. Cardiovasc Diabetol. 2024. PMID: 38762719 Free PMC article.
Bariatric surgery, through beneficial effects on underlying mechanisms, improves cardiorenal and liver metabolic risk over an average of ten years of observation: A longitudinal and a case-control study.
Kokkinos A, Tsilingiris D, Simati S, Stefanakis K, Angelidi AM, Tentolouris N, Anastasiou IA, Connelly MA, Alexandrou A, Mantzoros CS. Kokkinos A, et al. Among authors: stefanakis k. Metabolism. 2024 Mar;152:155773. doi: 10.1016/j.metabol.2023.155773. Epub 2024 Jan 3. Metabolism. 2024. PMID: 38181882
Recent research advances in metabolism, clinical and experimental.
Boutari C, Kokkorakis M, Stefanakis K, Valenzuela-Vallejo L, Axarloglou E, Volčanšek Š, Chakhtoura M, Mantzoros CS. Boutari C, et al. Among authors: stefanakis k. Metabolism. 2023 Dec;149:155722. doi: 10.1016/j.metabol.2023.155722. Epub 2023 Nov 4. Metabolism. 2023. PMID: 37931873 No abstract available.
Circulating levels of proglucagon-derived peptides are differentially regulated by the glucagon-like peptide-1 agonist liraglutide and the centrally acting naltrexone/bupropion and can predict future weight loss and metabolic improvements: A 6-month long interventional study.
Stefanakis K, Kokkinos A, Argyrakopoulou G, Konstantinidou SK, Simati S, Kouvari M, Kumar A, Kalra B, Kumar M, Bontozoglou N, Kyriakopoulou K, Mantzoros CS. Stefanakis K, et al. Diabetes Obes Metab. 2023 Sep;25(9):2561-2574. doi: 10.1111/dom.15141. Epub 2023 May 29. Diabetes Obes Metab. 2023. PMID: 37246799
PCSK9 and ANGPTL3 levels correlate with hyperlipidemia in HIV-lipoatrophy, are regulated by fasting and are not affected by leptin administered in physiologic or pharmacologic doses.
Bouzoni E, Perakakis N, Connelly MA, Angelidi AM, Pilitsi E, Farr O, Stefanakis K, Mantzoros CS. Bouzoni E, et al. Among authors: stefanakis k. Metabolism. 2022 Sep;134:155265. doi: 10.1016/j.metabol.2022.155265. Epub 2022 Jul 9. Metabolism. 2022. PMID: 35820631 Clinical Trial.
Effect of the glucagon-like peptide-1 analogue liraglutide versus placebo treatment on circulating proglucagon-derived peptides that mediate improvements in body weight, insulin secretion and action: A randomized controlled trial.
Kim SH, Abbasi F, Nachmanoff C, Stefanakis K, Kumar A, Kalra B, Savjani G, Mantzoros CS. Kim SH, et al. Among authors: stefanakis k. Diabetes Obes Metab. 2021 Feb;23(2):489-498. doi: 10.1111/dom.14242. Epub 2020 Nov 19. Diabetes Obes Metab. 2021. PMID: 33140542 Free PMC article. Clinical Trial.
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