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Navigating the Landscape of Translational Geroscience in Canada: A Comprehensive Evaluation of Current Progress and Future Directions.
Hajj-Boutros G, Faust A, Muscedere J, Kim P, Abumrad N, Chevalier S, Aubertin-Leheudre M, Bergman H, Bowdish D, Burford J, Carrington-Lawrence S, Côté H, Dawe DE, Barreto PS, Farrelly C, Fowler R, Gouspillou G, Harrington L, Lautrup S, Howlett S, Imani M, Kirkland J, Kuchel G, Mallette FA, Morais JA, Newman JC, Pullman D, Sierra F, Van Raamsdonk J, Watt J, Rylett RJ, Duque G. Hajj-Boutros G, et al. Among authors: kirkland j. J Gerontol A Biol Sci Med Sci. 2024 Mar 15:glae069. doi: 10.1093/gerona/glae069. Online ahead of print. J Gerontol A Biol Sci Med Sci. 2024. PMID: 38486371
Past and Future Directions for Research on Cellular Senescence.
Zhu Y, Anastasiadis ZP, Espindola Netto JM, Evans T, Tchkonia T, Kirkland JL. Zhu Y, et al. Cold Spring Harb Perspect Med. 2024 Feb 1;14(2):a041205. doi: 10.1101/cshperspect.a041205. Cold Spring Harb Perspect Med. 2024. PMID: 37734865 Review.
Cellular Senescence in Human Skin Aging: Leveraging Senotherapeutics.
Wyles SP, Carruthers JD, Dashti P, Yu G, Yap JQ, Gingery A, Tchkonia T, Kirkland J. Wyles SP, et al. Among authors: kirkland j. Gerontology. 2024;70(1):7-14. doi: 10.1159/000534756. Epub 2023 Oct 25. Gerontology. 2024. PMID: 37879300 Review.
Caloric Restriction Intervention Alters Specific Circulating Biomarkers of the Senescence-Associated Secretome in Middle-Aged and Older Adults With Obesity and Prediabetes in an 18-Week Randomized Controlled Trial.
Justice JN, Leng XI, LeBrasseur NK, Tchkonia T, Kirkland JL, Mitin N, Liu Y, Kritchevsky SB, Nicklas BJ, Ding J. Justice JN, et al. Among authors: kirkland jl. J Gerontol A Biol Sci Med Sci. 2024 Jan 1;79(1):glad214. doi: 10.1093/gerona/glad214. J Gerontol A Biol Sci Med Sci. 2024. PMID: 37738560 Clinical Trial.
Cellular senescence in brain aging and cognitive decline.
Shafqat A, Khan S, Omer MH, Niaz M, Albalkhi I, AlKattan K, Yaqinuddin A, Tchkonia T, Kirkland JL, Hashmi SK. Shafqat A, et al. Front Aging Neurosci. 2023 Nov 23;15:1281581. doi: 10.3389/fnagi.2023.1281581. eCollection 2023. Front Aging Neurosci. 2023. PMID: 38076538 Free PMC article. Review.
A chronic wound model to investigate skin cellular senescence.
Wyles SP, Dashti P, Pirtskhalava T, Tekin B, Inman C, Gomez LS, Lagnado AB, Prata L, Jurk D, Passos JF, Tchkonia T, Kirkland JL. Wyles SP, et al. Aging (Albany NY). 2023 Apr 21;15(8):2852-2862. doi: 10.18632/aging.204667. Epub 2023 Apr 21. Aging (Albany NY). 2023. PMID: 37086260 Free PMC article.
Clinical validation of C12FDG as a marker associated with senescence and osteoarthritic phenotypes.
Hambright WS, Duke VR, Goff AD, Goff AW, Minas LT, Kloser H, Gao X, Huard C, Guo P, Lu A, Mitchell J, Mullen M, Su C, Tchkonia T, Espindola Netto JM, Robbins PD, Niedernhofer LJ, Kirkland JL, Bahney CS, Philippon M, Huard J. Hambright WS, et al. Among authors: kirkland jl. Aging Cell. 2024 May;23(5):e14113. doi: 10.1111/acel.14113. Epub 2024 May 6. Aging Cell. 2024. PMID: 38708778 Free PMC article.
654 results